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Endoplasmic reticulum stress enhances γ-secretase activity.
Ohta K, Mizuno A, Li S, Itoh M, Ueda M, Ohta E, Hida Y, Wang MX, Furoi M, Tsuzuki Y, Sobajima M, Bohmoto Y, Fukushima T, Kobori M, Inuzuka T, Nakagawa T. Ohta K, et al. Among authors: ohta e. Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):362-6. doi: 10.1016/j.bbrc.2011.11.042. Epub 2011 Nov 16. Biochem Biophys Res Commun. 2011. PMID: 22115781
ATF4 regulates gamma-secretase activity during amino acid imbalance.
Mitsuda T, Hayakawa Y, Itoh M, Ohta K, Nakagawa T. Mitsuda T, et al. Among authors: ohta k. Biochem Biophys Res Commun. 2007 Jan 19;352(3):722-7. doi: 10.1016/j.bbrc.2006.11.075. Epub 2006 Nov 27. Biochem Biophys Res Commun. 2007. PMID: 17141186
Polyglutamine expansion disturbs the endoplasmic reticulum formation, leading to caspase-7 activation through Bax.
Ueda M, Li S, Itoh M, Hayakawa-Yano Y, Wang MX, Hayakawa M, Hasebe-Matsubara R, Ohta K, Ohta E, Mizuno A, Hida Y, Matsumoto M, Chen H, Nakagawa T. Ueda M, et al. Among authors: ohta e, ohta k. Biochem Biophys Res Commun. 2014 Jan 24;443(4):1232-8. doi: 10.1016/j.bbrc.2013.12.114. Epub 2014 Jan 2. Biochem Biophys Res Commun. 2014. PMID: 24388981
Quercetin reduces eIF2α phosphorylation by GADD34 induction.
Hayakawa M, Itoh M, Ohta K, Li S, Ueda M, Wang MX, Nishida E, Islam S, Suzuki C, Ohzawa K, Kobori M, Inuzuka T, Nakagawa T. Hayakawa M, et al. Among authors: ohta k. Neurobiol Aging. 2015 Sep;36(9):2509-18. doi: 10.1016/j.neurobiolaging.2015.05.006. Epub 2015 May 15. Neurobiol Aging. 2015. PMID: 26070242
CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes.
Wang MX, Itoh M, Li S, Hida Y, Ohta K, Hayakawa M, Nishida E, Ueda M, Islam S, Tana, Nakagawa T. Wang MX, et al. Among authors: ohta k. Biochem Biophys Res Commun. 2016 Jan 29;470(1):48-53. doi: 10.1016/j.bbrc.2015.12.102. Epub 2015 Dec 29. Biochem Biophys Res Commun. 2016. PMID: 26740177
2,894 results