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Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes.
Mohme M, Schliffke S, Maire CL, Rünger A, Glau L, Mende KC, Matschke J, Gehbauer C, Akyüz N, Zapf S, Holz M, Schaper M, Martens T, Schmidt NO, Peine S, Westphal M, Binder M, Tolosa E, Lamszus K. Mohme M, et al. Among authors: schliffke s. Clin Cancer Res. 2018 Sep 1;24(17):4187-4200. doi: 10.1158/1078-0432.CCR-17-2617. Epub 2018 Feb 14. Clin Cancer Res. 2018. PMID: 29444930
Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape.
Mohme M, Maire CL, Schliffke S, Joosse SA, Alawi M, Matschke J, Schüller U, Dierlamm J, Martens T, Pantel K, Riethdorf S, Lamszus K, Westphal M. Mohme M, et al. Among authors: schliffke s. Acta Neuropathol Commun. 2020 Mar 9;8(1):28. doi: 10.1186/s40478-020-00906-9. Acta Neuropathol Commun. 2020. PMID: 32151286 Free PMC article.
T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker.
Akyüz N, Brandt A, Stein A, Schliffke S, Mährle T, Quidde J, Goekkurt E, Loges S, Haalck T, Ford CT, Asemissen AM, Thiele B, Radloff J, Thenhausen T, Krohn-Grimberghe A, Bokemeyer C, Binder M. Akyüz N, et al. Among authors: schliffke s. Int J Cancer. 2017 Jun 1;140(11):2535-2544. doi: 10.1002/ijc.30549. Epub 2017 Mar 6. Int J Cancer. 2017. PMID: 27925177 Free article.
T cell receptor next-generation sequencing reveals cancer-associated repertoire metrics and reconstitution after chemotherapy in patients with hematological and solid tumors.
Simnica D, Akyüz N, Schliffke S, Mohme M, V Wenserski L, Mährle T, Fanchi LF, Lamszus K, Binder M. Simnica D, et al. Among authors: schliffke s. Oncoimmunology. 2019 Jul 25;8(11):e1644110. doi: 10.1080/2162402X.2019.1644110. eCollection 2019. Oncoimmunology. 2019. PMID: 31646093 Free PMC article.
19 results