Brown DR - Search Results

1

Metal attenuating therapies in neurodegenerative disease.

Mot AI, Wedd AG, Sinclair L, Brown DR, Collins SJ, Brazier MW. Mot AI, et al. Among authors: brown dr. Expert Rev Neurother. 2011 Dec;11(12):1717-45. doi: 10.1586/ern.11.170. Expert Rev Neurother. 2011. PMID: 22091597 Review.

2

The effects of prion protein expression on metal metabolism.

Kralovicova S, Fontaine SN, Alderton A, Alderman J, Ragnarsdottir KV, Collins SJ, Brown DR. Kralovicova S, et al. Among authors: brown dr. Mol Cell Neurosci. 2009 Jun;41(2):135-47. doi: 10.1016/j.mcn.2009.02.002. Epub 2009 Feb 21. Mol Cell Neurosci. 2009. PMID: 19233277

3

Mouse galectin-1 inhibits the toxicity of glutamate by modifying NR1 NMDA receptor expression.

Lekishvili T, Hesketh S, Brazier MW, Brown DR. Lekishvili T, et al. Among authors: brown dr. Eur J Neurosci. 2006 Dec;24(11):3017-25. doi: 10.1111/j.1460-9568.2006.05207.x. Eur J Neurosci. 2006. PMID: 17156363

4

Prion protein does not redox-silence Cu2+, but is a sacrificial quencher of hydroxyl radicals.

Nadal RC, Abdelraheim SR, Brazier MW, Rigby SE, Brown DR, Viles JH. Nadal RC, et al. Among authors: brown dr. Free Radic Biol Med. 2007 Jan 1;42(1):79-89. doi: 10.1016/j.freeradbiomed.2006.09.019. Epub 2006 Sep 27. Free Radic Biol Med. 2007. PMID: 17157195

5

Dynamics of a truncated prion protein, PrP(113-231), from (15)N NMR relaxation: order parameters calculated and slow conformational fluctuations localized to a distinct region.

O'Sullivan DB, Jones CE, Abdelraheim SR, Brazier MW, Toms H, Brown DR, Viles JH. O'Sullivan DB, et al. Among authors: brown dr. Protein Sci. 2009 Feb;18(2):410-23. doi: 10.1002/pro.44. Protein Sci. 2009. PMID: 19173221 Free PMC article.

6

Manganese binding to the prion protein.

Brazier MW, Davies P, Player E, Marken F, Viles JH, Brown DR. Brazier MW, et al. Among authors: brown dr. J Biol Chem. 2008 May 9;283(19):12831-9. doi: 10.1074/jbc.M709820200. Epub 2008 Mar 10. J Biol Chem. 2008. PMID: 18332141 Free article.

7

High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation.

Zerovnik E, Skerget K, Tusek-Znidaric M, Loeschner C, Brazier MW, Brown DR. Zerovnik E, et al. Among authors: brown dr. FEBS J. 2006 Sep;273(18):4250-63. doi: 10.1111/j.1742-4658.2006.05426.x. FEBS J. 2006. PMID: 16939620 Free article.

8

NMR characterization of the pH 4 beta-intermediate of the prion protein: the N-terminal half of the protein remains unstructured and retains a high degree of flexibility.

O'Sullivan DB, Jones CE, Abdelraheim SR, Thompsett AR, Brazier MW, Toms H, Brown DR, Viles JH. O'Sullivan DB, et al. Among authors: brown dr. Biochem J. 2007 Jan 15;401(2):533-40. doi: 10.1042/BJ20060668. Biochem J. 2007. PMID: 16958619 Free PMC article.

9

Prion disease: A loss of antioxidant function?

Wong BS, Pan T, Liu T, Li R, Petersen RB, Jones IM, Gambetti P, Brown DR, Sy MS. Wong BS, et al. Among authors: brown dr. Biochem Biophys Res Commun. 2000 Aug 28;275(2):249-52. doi: 10.1006/bbrc.2000.3158. Biochem Biophys Res Commun. 2000. PMID: 10964653 Review.

10

Aberrant metal binding by prion protein in human prion disease.

Wong BS, Chen SG, Colucci M, Xie Z, Pan T, Liu T, Li R, Gambetti P, Sy MS, Brown DR. Wong BS, et al. Among authors: brown dr. J Neurochem. 2001 Sep;78(6):1400-8. doi: 10.1046/j.1471-4159.2001.00522.x. J Neurochem. 2001. PMID: 11579148 Free article.

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