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An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria.
Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Tasken K, Scott JD. Means CK, et al. Among authors: tasken k. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):E1227-35. doi: 10.1073/pnas.1107182108. Epub 2011 Nov 14. Proc Natl Acad Sci U S A. 2011. PMID: 22084075 Free PMC article.
Creating order from chaos: cellular regulation by kinase anchoring.
Scott JD, Dessauer CW, Taskén K. Scott JD, et al. Among authors: tasken k. Annu Rev Pharmacol Toxicol. 2013;53:187-210. doi: 10.1146/annurev-pharmtox-011112-140204. Epub 2012 Oct 8. Annu Rev Pharmacol Toxicol. 2013. PMID: 23043438 Free PMC article. Review.
Molecular basis of AKAP specificity for PKA regulatory subunits.
Gold MG, Lygren B, Dokurno P, Hoshi N, McConnachie G, Taskén K, Carlson CR, Scott JD, Barford D. Gold MG, et al. Among authors: tasken k. Mol Cell. 2006 Nov 3;24(3):383-95. doi: 10.1016/j.molcel.2006.09.006. Mol Cell. 2006. PMID: 17081989 Free article.
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
McCahill A, McSorley T, Huston E, Hill EV, Lynch MJ, Gall I, Keryer G, Lygren B, Tasken K, van Heeke G, Houslay MD. McCahill A, et al. Among authors: tasken k. Cell Signal. 2005 Sep;17(9):1158-73. doi: 10.1016/j.cellsig.2005.04.003. Cell Signal. 2005. PMID: 15905070
324 results