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An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria.
Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Tasken K, Scott JD. Means CK, et al. Among authors: murphy an. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):E1227-35. doi: 10.1073/pnas.1107182108. Epub 2011 Nov 14. Proc Natl Acad Sci U S A. 2011. PMID: 22084075 Free PMC article.
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.
Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy AN. Divakaruni AS, et al. Among authors: murphy an. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5422-7. doi: 10.1073/pnas.1303360110. Epub 2013 Mar 19. Proc Natl Acad Sci U S A. 2013. PMID: 23513224 Free PMC article.
Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS.
Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW. Da Cruz S, et al. Among authors: murphy an. Cell Metab. 2012 May 2;15(5):778-86. doi: 10.1016/j.cmet.2012.03.019. Cell Metab. 2012. PMID: 22560226 Free PMC article.
125 results