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gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway.
Fava G, Marucci L, Glaser S, Francis H, De Morrow S, Benedetti A, Alvaro D, Venter J, Meininger C, Patel T, Taffetani S, Marzioni M, Summers R, Reichenbach R, Alpini G. Fava G, et al. Cancer Res. 2005 Dec 15;65(24):11437-46. doi: 10.1158/0008-5472.CAN-05-1470. Cancer Res. 2005. PMID: 16357152
The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway.
DeMorrow S, Francis H, Gaudio E, Venter J, Franchitto A, Kopriva S, Onori P, Mancinelli R, Frampton G, Coufal M, Mitchell B, Vaculin B, Alpini G. DeMorrow S, et al. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1150-8. doi: 10.1152/ajpgi.90455.2008. Epub 2008 Oct 2. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18832445 Free PMC article.
Increased local dopamine secretion has growth-promoting effects in cholangiocarcinoma.
Coufal M, Invernizzi P, Gaudio E, Bernuzzi F, Frampton GA, Onori P, Franchitto A, Carpino G, Ramirez JC, Alvaro D, Marzioni M, Battisti G, Benedetti A, DeMorrow S. Coufal M, et al. Among authors: demorrow s. Int J Cancer. 2010 May 1;126(9):2112-22. doi: 10.1002/ijc.24909. Int J Cancer. 2010. PMID: 19795457 Free PMC article.
H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.
Francis H, Onori P, Gaudio E, Franchitto A, DeMorrow S, Venter J, Kopriva S, Carpino G, Mancinelli R, White M, Meng F, Vetuschi A, Sferra R, Alpini G. Francis H, et al. Among authors: demorrow s. Mol Cancer Res. 2009 Oct;7(10):1704-13. doi: 10.1158/1541-7786.MCR-09-0261. Epub 2009 Oct 13. Mol Cancer Res. 2009. PMID: 19825989 Free PMC article.
Recent advances in the regulation of cholangiocarcinoma growth.
Francis H, Alpini G, DeMorrow S. Francis H, et al. Among authors: demorrow s. Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G1-9. doi: 10.1152/ajpgi.00114.2010. Epub 2010 Apr 29. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 20430870 Free PMC article. Review.
120 results