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Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
Lonardo E, Hermann PC, Mueller MT, Huber S, Balic A, Miranda-Lorenzo I, Zagorac S, Alcala S, Rodriguez-Arabaolaza I, Ramirez JC, Torres-Ruíz R, Garcia E, Hidalgo M, Cebrián DÁ, Heuchel R, Löhr M, Berger F, Bartenstein P, Aicher A, Heeschen C. Lonardo E, et al. Among authors: miranda lorenzo i. Cell Stem Cell. 2011 Nov 4;9(5):433-46. doi: 10.1016/j.stem.2011.10.001. Cell Stem Cell. 2011. PMID: 22056140 Free article.
Pancreatic cancer stem cells: new insights and perspectives.
Dorado J, Lonardo E, Miranda-Lorenzo I, Heeschen C. Dorado J, et al. Among authors: miranda lorenzo i. J Gastroenterol. 2011 Aug;46(8):966-73. doi: 10.1007/s00535-011-0422-x. Epub 2011 Jun 23. J Gastroenterol. 2011. PMID: 21698355 Review.
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.
Cioffi M, Trabulo SM, Sanchez-Ripoll Y, Miranda-Lorenzo I, Lonardo E, Dorado J, Reis Vieira C, Ramirez JC, Hidalgo M, Aicher A, Hahn S, Sainz B Jr, Heeschen C. Cioffi M, et al. Among authors: miranda lorenzo i. Gut. 2015 Dec;64(12):1936-48. doi: 10.1136/gutjnl-2014-308470. Epub 2015 Apr 17. Gut. 2015. PMID: 25887381 Free PMC article.
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.
Miranda-Lorenzo I, Dorado J, Lonardo E, Alcala S, Serrano AG, Clausell-Tormos J, Cioffi M, Megias D, Zagorac S, Balic A, Hidalgo M, Erkan M, Kleeff J, Scarpa A, Sainz B Jr, Heeschen C. Miranda-Lorenzo I, et al. Nat Methods. 2014 Nov;11(11):1161-9. doi: 10.1038/nmeth.3112. Epub 2014 Sep 28. Nat Methods. 2014. PMID: 25262208
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Sainz B Jr, Alcala S, Garcia E, Sanchez-Ripoll Y, Azevedo MM, Cioffi M, Tatari M, Miranda-Lorenzo I, Hidalgo M, Gomez-Lopez G, Cañamero M, Erkan M, Kleeff J, García-Silva S, Sancho P, Hermann PC, Heeschen C. Sainz B Jr, et al. Among authors: miranda lorenzo i. Gut. 2015 Dec;64(12):1921-35. doi: 10.1136/gutjnl-2014-308935. Epub 2015 Apr 3. Gut. 2015. PMID: 25841238
Intracellular Autofluorescence as a New Biomarker for Cancer Stem Cells in Glioblastoma.
Vieira de Castro J, S Gonçalves C, P Martins E, Miranda-Lorenzo I, T Cerqueira M, Longatto-Filho A, A Pinto A, L Reis R, Sousa N, Heeschen C, M Costa B. Vieira de Castro J, et al. Among authors: miranda lorenzo i. Cancers (Basel). 2021 Feb 16;13(4):828. doi: 10.3390/cancers13040828. Cancers (Basel). 2021. PMID: 33669350 Free PMC article.
Primate genome gain and loss: a bone dysplasia, muscular dystrophy, and bone cancer syndrome resulting from mutated retroviral-derived MTAP transcripts.
Camacho-Vanegas O, Camacho SC, Till J, Miranda-Lorenzo I, Terzo E, Ramirez MC, Schramm V, Cordovano G, Watts G, Mehta S, Kimonis V, Hoch B, Philibert KD, Raabe CA, Bishop DF, Glucksman MJ, Martignetti JA. Camacho-Vanegas O, et al. Among authors: miranda lorenzo i. Am J Hum Genet. 2012 Apr 6;90(4):614-27. doi: 10.1016/j.ajhg.2012.02.024. Epub 2012 Mar 29. Am J Hum Genet. 2012. PMID: 22464254 Free PMC article.