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Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α.
A M, Wales TE, Zhou H, Draga-Coletă SV, Gorgulla C, Blackmore KA, Mittenbühler MJ, Kim CR, Bogoslavski D, Zhang Q, Wang ZF, Jedrychowski MP, Seo HS, Song K, Xu AZ, Sebastian L, Gygi SP, Arthanari H, Dhe-Paganon S, Griffin PR, Engen JR, Spiegelman BM. A M, et al. Among authors: jedrychowski mp. Mol Cell. 2023 Jun 1;83(11):1903-1920.e12. doi: 10.1016/j.molcel.2023.05.008. Mol Cell. 2023. PMID: 37267907 Free PMC article.
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer's disease.
Yin Z, Herron S, Silveira S, Kleemann K, Gauthier C, Mallah D, Cheng Y, Margeta MA, Pitts KM, Barry JL, Subramanian A, Shorey H, Brandao W, Durao A, Delpech JC, Madore C, Jedrychowski M, Ajay AK, Murugaiyan G, Hersh SW, Ikezu S, Ikezu T, Butovsky O. Yin Z, et al. Nat Neurosci. 2023 Jul;26(7):1196-1207. doi: 10.1038/s41593-023-01355-y. Epub 2023 Jun 8. Nat Neurosci. 2023. PMID: 37291336
Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues.
Mittenbühler MJ, Jedrychowski MP, Van Vranken JG, Sprenger HG, Wilensky S, Dumesic PA, Sun Y, Tartaglia A, Bogoslavski D, A M, Xiao H, Blackmore KA, Reddy A, Gygi SP, Chouchani ET, Spiegelman BM. Mittenbühler MJ, et al. Among authors: jedrychowski mp. Cell Metab. 2023 Mar 7;35(3):535-549.e7. doi: 10.1016/j.cmet.2022.12.014. Epub 2023 Jan 20. Cell Metab. 2023. PMID: 36681077 Free PMC article.
Cellular spelunking: exploring adipocyte caveolae.
Pilch PF, Souto RP, Liu L, Jedrychowski MP, Berg EA, Costello CE, Gygi SP. Pilch PF, et al. Among authors: jedrychowski mp. J Lipid Res. 2007 Oct;48(10):2103-11. doi: 10.1194/jlr.R700009-JLR200. Epub 2007 May 11. J Lipid Res. 2007. PMID: 17496267 Free article. Review.
Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes.
Hong S, Song W, Zushin PH, Liu B, Jedrychowski MP, Mina AI, Deng Z, Cabarkapa D, Hall JA, Palmer CJ, Aliakbarian H, Szpyt J, Gygi SP, Tavakkoli A, Lynch L, Perrimon N, Banks AS. Hong S, et al. Among authors: jedrychowski mp. Mol Metab. 2018 Jun;12:25-38. doi: 10.1016/j.molmet.2018.03.012. Epub 2018 Mar 29. Mol Metab. 2018. PMID: 29661693 Free PMC article.
The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT-liver communication.
Sponton CH, Hosono T, Taura J, Jedrychowski MP, Yoneshiro T, Wang Q, Takahashi M, Matsui Y, Ikeda K, Oguri Y, Tajima K, Shinoda K, Pradhan RN, Chen Y, Brown Z, Roberts LS, Ward CC, Taoka H, Yokoyama Y, Watanabe M, Karasawa H, Nomura DK, Kajimura S. Sponton CH, et al. Among authors: jedrychowski mp. EMBO Rep. 2020 Sep 3;21(9):e49828. doi: 10.15252/embr.201949828. Epub 2020 Jul 16. EMBO Rep. 2020. PMID: 32672883 Free PMC article.
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP. Beausoleil SA, et al. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12130-5. doi: 10.1073/pnas.0404720101. Epub 2004 Aug 9. Proc Natl Acad Sci U S A. 2004. PMID: 15302935 Free PMC article.
105 results