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PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.
Hikata T, Takaishi H, Takito J, Hakozaki A, Furukawa M, Uchikawa S, Kimura T, Okada Y, Matsumoto M, Yoshimura A, Nishimura R, Reddy SV, Asahara H, Toyama Y. Hikata T, et al. Among authors: uchikawa s. Blood. 2009 Mar 5;113(10):2202-12. doi: 10.1182/blood-2008-06-162594. Epub 2008 Oct 24. Blood. 2009. PMID: 18952894 Free PMC article.
IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.
Furukawa M, Takaishi H, Takito J, Yoda M, Sakai S, Hikata T, Hakozaki A, Uchikawa S, Matsumoto M, Chiba K, Kimura T, Okada Y, Matsuo K, Yoshida H, Toyama Y. Furukawa M, et al. Among authors: uchikawa s. J Immunol. 2009 Aug 15;183(4):2397-406. doi: 10.4049/jimmunol.0802091. Epub 2009 Jul 20. J Immunol. 2009. PMID: 19620301
137 results