Davis M - Search Results

1

Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer.

Gaur S, Chen L, Yen T, Wang Y, Zhou B, Davis M, Yen Y. Gaur S, et al. Among authors: davis m. Nanomedicine. 2012 Jul;8(5):721-30. doi: 10.1016/j.nano.2011.09.007. Epub 2011 Oct 25. Nanomedicine. 2012. PMID: 22033079

2

Pharmacodynamic and pharmacogenomic study of the nanoparticle conjugate of camptothecin CRLX101 for the treatment of cancer.

Gaur S, Wang Y, Kretzner L, Chen L, Yen T, Wu X, Yuan YC, Davis M, Yen Y. Gaur S, et al. Among authors: davis m. Nanomedicine. 2014 Oct;10(7):1477-86. doi: 10.1016/j.nano.2014.04.003. Epub 2014 Apr 22. Nanomedicine. 2014. PMID: 24768630

3

Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models.

Numbenjapon T, Wang J, Colcher D, Schluep T, Davis ME, Duringer J, Kretzner L, Yen Y, Forman SJ, Raubitschek A. Numbenjapon T, et al. Clin Cancer Res. 2009 Jul 1;15(13):4365-73. doi: 10.1158/1078-0432.CCR-08-2619. Epub 2009 Jun 23. Clin Cancer Res. 2009. PMID: 19549776 Free PMC article.

4

First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies.

Weiss GJ, Chao J, Neidhart JD, Ramanathan RK, Bassett D, Neidhart JA, Choi CHJ, Chow W, Chung V, Forman SJ, Garmey E, Hwang J, Kalinoski DL, Koczywas M, Longmate J, Melton RJ, Morgan R, Oliver J, Peterkin JJ, Ryan JL, Schluep T, Synold TW, Twardowski P, Davis ME, Yen Y. Weiss GJ, et al. Among authors: davis me. Invest New Drugs. 2013 Aug;31(4):986-1000. doi: 10.1007/s10637-012-9921-8. Epub 2013 Feb 9. Invest New Drugs. 2013. PMID: 23397498 Free PMC article. Clinical Trial.

5

CRLX101 nanoparticles localize in human tumors and not in adjacent, nonneoplastic tissue after intravenous dosing.

Clark AJ, Wiley DT, Zuckerman JE, Webster P, Chao J, Lin J, Yen Y, Davis ME. Clark AJ, et al. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3850-4. doi: 10.1073/pnas.1603018113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001839 Free PMC article.

6

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers.

Chen YF, Wang YH, Lei CS, Changou CA, Davis ME, Yen Y. Chen YF, et al. J Biomed Sci. 2019 Oct 23;26(1):85. doi: 10.1186/s12929-019-0583-0. J Biomed Sci. 2019. PMID: 31647037 Free PMC article.

7

Pilot trial of CRLX101 in patients with advanced, chemotherapy-refractory gastroesophageal cancer.

Chao J, Lin J, Frankel P, Clark AJ, Wiley DT, Garmey E, Fakih M, Lim D, Chung V, Luevanos E, Eliasof S, Davis ME, Yen Y. Chao J, et al. Among authors: davis me. J Gastrointest Oncol. 2017 Dec;8(6):962-969. doi: 10.21037/jgo.2017.08.10. J Gastrointest Oncol. 2017. PMID: 29299355 Free PMC article.

8

Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA.

Zuckerman JE, Gritli I, Tolcher A, Heidel JD, Lim D, Morgan R, Chmielowski B, Ribas A, Davis ME, Yen Y. Zuckerman JE, et al. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11449-54. doi: 10.1073/pnas.1411393111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049380 Free PMC article. Clinical Trial.

9

Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo.

Heidel JD, Liu JY, Yen Y, Zhou B, Heale BS, Rossi JJ, Bartlett DW, Davis ME. Heidel JD, et al. Clin Cancer Res. 2007 Apr 1;13(7):2207-15. doi: 10.1158/1078-0432.CCR-06-2218. Clin Cancer Res. 2007. PMID: 17404105

10

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth.

Rahman MA, Amin AR, Wang X, Zuckerman JE, Choi CH, Zhou B, Wang D, Nannapaneni S, Koenig L, Chen Z, Chen ZG, Yen Y, Davis ME, Shin DM. Rahman MA, et al. Among authors: davis me. J Control Release. 2012 May 10;159(3):384-92. doi: 10.1016/j.jconrel.2012.01.045. Epub 2012 Feb 8. J Control Release. 2012. PMID: 22342644 Free PMC article.

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