Knowles J - Search Results

1

Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing.

Small BG, McColl BW, Allmendinger R, Pahle J, López-Castejón G, Rothwell NJ, Knowles J, Mendes P, Brough D, Kell DB. Small BG, et al. Among authors: knowles j. Nat Chem Biol. 2011 Oct 23;7(12):902-8. doi: 10.1038/nchembio.689. Nat Chem Biol. 2011. PMID: 22020553 Free PMC article.

2

Multiobjective optimization in bioinformatics and computational biology.

Handl J, Kell DB, Knowles J. Handl J, et al. Among authors: knowles j. IEEE/ACM Trans Comput Biol Bioinform. 2007 Apr-Jun;4(2):279-92. doi: 10.1109/TCBB.2007.070203. IEEE/ACM Trans Comput Biol Bioinform. 2007. PMID: 17473320 Free article. Review.

3

On handling ephemeral resource constraints in evolutionary search.

Allmendinger R, Knowles J. Allmendinger R, et al. Among authors: knowles j. Evol Comput. 2013 Fall;21(3):497-531. doi: 10.1162/EVCO_a_00097. Epub 2013 Jun 19. Evol Comput. 2013. PMID: 23163779

4

Exploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing.

O'Hagan S, Knowles J, Kell DB. O'Hagan S, et al. Among authors: knowles j. PLoS One. 2012;7(11):e48862. doi: 10.1371/journal.pone.0048862. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185279 Free PMC article.

5

In silico modelling of directed evolution: Implications for experimental design and stepwise evolution.

Wedge DC, Rowe W, Kell DB, Knowles J. Wedge DC, et al. Among authors: knowles j. J Theor Biol. 2009 Mar 7;257(1):131-41. doi: 10.1016/j.jtbi.2008.11.005. Epub 2008 Nov 17. J Theor Biol. 2009. PMID: 19073195

6

Analysis of aptamer sequence activity relationships.

Platt M, Rowe W, Knowles J, Day PJ, Kell DB. Platt M, et al. Among authors: knowles j. Integr Biol (Camb). 2009 Jan;1(1):116-22. doi: 10.1039/b814892a. Epub 2008 Nov 12. Integr Biol (Camb). 2009. PMID: 20023798

7

Analysis of a complete DNA-protein affinity landscape.

Rowe W, Platt M, Wedge DC, Day PJ, Kell DB, Knowles J. Rowe W, et al. Among authors: knowles j. J R Soc Interface. 2010 Mar 6;7(44):397-408. doi: 10.1098/rsif.2009.0193. Epub 2009 Jul 22. J R Soc Interface. 2010. PMID: 19625306 Free PMC article.

8

Computational cluster validation in post-genomic data analysis.

Handl J, Knowles J, Kell DB. Handl J, et al. Among authors: knowles j. Bioinformatics. 2005 Aug 1;21(15):3201-12. doi: 10.1093/bioinformatics/bti517. Epub 2005 May 24. Bioinformatics. 2005. PMID: 15914541 Review.

9

Predictive models for population performance on real biological fitness landscapes.

Rowe W, Wedge DC, Platt M, Kell DB, Knowles J. Rowe W, et al. Among authors: knowles j. Bioinformatics. 2010 Sep 1;26(17):2145-52. doi: 10.1093/bioinformatics/btq353. Epub 2010 Jul 17. Bioinformatics. 2010. PMID: 20639542

10

Closed-loop, multiobjective optimization of analytical instrumentation: gas chromatography/time-of-flight mass spectrometry of the metabolomes of human serum and of yeast fermentations.

O'Hagan S, Dunn WB, Brown M, Knowles JD, Kell DB. O'Hagan S, et al. Anal Chem. 2005 Jan 1;77(1):290-303. doi: 10.1021/ac049146x. Anal Chem. 2005. PMID: 15623308

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