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Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.
Nat Protoc. 2011 Oct 20;6(11):1748-60. doi: 10.1038/nprot.2011.386.
Nat Protoc. 2011.
PMID: 22015845
Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements.
Schröder R, Janssen N, Schmidt J, Kebig A, Merten N, Hennen S, Müller A, Blättermann S, Mohr-Andrä M, Zahn S, Wenzel J, Smith NJ, Gomeza J, Drewke C, Milligan G, Mohr K, Kostenis E.
Schröder R, et al. Among authors: blattermann s.
Nat Biotechnol. 2010 Sep;28(9):943-9. doi: 10.1038/nbt.1671. Epub 2010 Aug 15.
Nat Biotechnol. 2010.
PMID: 20711173
Free article.
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Decoding signaling and function of the orphan G protein-coupled receptor GPR17 with a small-molecule agonist.
Hennen S, Wang H, Peters L, Merten N, Simon K, Spinrath A, Blättermann S, Akkari R, Schrage R, Schröder R, Schulz D, Vermeiren C, Zimmermann K, Kehraus S, Drewke C, Pfeifer A, König GM, Mohr K, Gillard M, Müller CE, Lu QR, Gomeza J, Kostenis E.
Hennen S, et al. Among authors: blattermann s.
Sci Signal. 2013 Oct 22;6(298):ra93. doi: 10.1126/scisignal.2004350.
Sci Signal. 2013.
PMID: 24150254
Free PMC article.
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A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.
Blättermann S, Peters L, Ottersbach PA, Bock A, Konya V, Weaver CD, Gonzalez A, Schröder R, Tyagi R, Luschnig P, Gäb J, Hennen S, Ulven T, Pardo L, Mohr K, Gütschow M, Heinemann A, Kostenis E.
Blättermann S, et al.
Nat Chem Biol. 2012 Jul;8(7):631-8. doi: 10.1038/nchembio.962. Epub 2012 May 27.
Nat Chem Biol. 2012.
PMID: 22634634
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The Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules.
Simon K, Hennen S, Merten N, Blättermann S, Gillard M, Kostenis E, Gomeza J.
Simon K, et al. Among authors: blattermann s.
J Biol Chem. 2016 Jan 8;291(2):705-18. doi: 10.1074/jbc.M115.683953. Epub 2015 Nov 30.
J Biol Chem. 2016.
PMID: 26620557
Free PMC article.
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GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils.
Balenga NA, Aflaki E, Kargl J, Platzer W, Schröder R, Blättermann S, Kostenis E, Brown AJ, Heinemann A, Waldhoer M.
Balenga NA, et al. Among authors: blattermann s.
Cell Res. 2011 Oct;21(10):1452-69. doi: 10.1038/cr.2011.60. Epub 2011 Apr 5.
Cell Res. 2011.
PMID: 21467997
Free PMC article.
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A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
Konya V, Blättermann S, Jandl K, Platzer W, Ottersbach PA, Marsche G, Gütschow M, Kostenis E, Heinemann A.
Konya V, et al. Among authors: blattermann s.
J Immunol. 2014 May 15;192(10):4774-82. doi: 10.4049/jimmunol.1302013. Epub 2014 Apr 14.
J Immunol. 2014.
PMID: 24733850
Clinical Trial.
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