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Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
Lolicato M, Nardini M, Gazzarrini S, Möller S, Bertinetti D, Herberg FW, Bolognesi M, Martin H, Fasolini M, Bertrand JA, Arrigoni C, Thiel G, Moroni A. Lolicato M, et al. Among authors: bertinetti d. J Biol Chem. 2011 Dec 30;286(52):44811-20. doi: 10.1074/jbc.M111.297606. Epub 2011 Oct 17. J Biol Chem. 2011. PMID: 22006928 Free PMC article.
Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.
Huang GY, Kim JJ, Reger AS, Lorenz R, Moon EW, Zhao C, Casteel DE, Bertinetti D, Vanschouwen B, Selvaratnam R, Pflugrath JW, Sankaran B, Melacini G, Herberg FW, Kim C. Huang GY, et al. Among authors: bertinetti d. Structure. 2014 Jan 7;22(1):116-24. doi: 10.1016/j.str.2013.09.021. Epub 2013 Nov 14. Structure. 2014. PMID: 24239458 Free PMC article.
Structure-guided design of selective Epac1 and Epac2 agonists.
Schwede F, Bertinetti D, Langerijs CN, Hadders MA, Wienk H, Ellenbroek JH, de Koning EJ, Bos JL, Herberg FW, Genieser HG, Janssen RA, Rehmann H. Schwede F, et al. Among authors: bertinetti d. PLoS Biol. 2015 Jan 20;13(1):e1002038. doi: 10.1371/journal.pbio.1002038. eCollection 2015 Jan. PLoS Biol. 2015. PMID: 25603503 Free PMC article.
Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress.
Kim JJ, Flueck C, Franz E, Sanabria-Figueroa E, Thompson E, Lorenz R, Bertinetti D, Baker DA, Herberg FW, Kim C. Kim JJ, et al. Among authors: bertinetti d. PLoS Pathog. 2015 Feb 3;11(2):e1004639. doi: 10.1371/journal.ppat.1004639. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25646845 Free PMC article.
Application of Synthetic Peptide Arrays To Uncover Cyclic Di-GMP Binding Motifs.
Düvel J, Bense S, Möller S, Bertinetti D, Schwede F, Morr M, Eckweiler D, Genieser HG, Jänsch L, Herberg FW, Frank R, Häussler S. Düvel J, et al. Among authors: bertinetti d. J Bacteriol. 2015 Aug 31;198(1):138-46. doi: 10.1128/JB.00377-15. Print 2016 Jan 1. J Bacteriol. 2015. PMID: 26324453 Free PMC article.
40 results