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Introduction of water into the heme distal side by Leu65 mutations of an oxygen sensor, YddV, generates verdoheme and carbon monoxide, exerting the heme oxygenase reaction.
Stranava M, Martínková M, Stiborová M, Man P, Kitanishi K, Muchová L, Vítek L, Martínek V, Shimizu T. Stranava M, et al. Among authors: kitanishi k. J Inorg Biochem. 2014 Nov;140:29-38. doi: 10.1016/j.jinorgbio.2014.06.010. Epub 2014 Jun 24. J Inorg Biochem. 2014. PMID: 25046385
Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, EcDOS and YddV, have profound effects on their flexibility.
Anzenbacher P, Marchal S, Palacký J, Anzenbacherová E, Domaschke T, Lange R, Shimizu T, Kitanishi K, Stranava M, Stiborová M, Martinkova M. Anzenbacher P, et al. Among authors: kitanishi k. FEBS J. 2014 Dec;281(23):5208-19. doi: 10.1111/febs.13060. Epub 2014 Oct 13. FEBS J. 2014. PMID: 25238584 Free article.
43 results