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Page 1
Non-canonical inflammasome activation targets caspase-11.
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, Newton K, Qu Y, Liu J, Heldens S, Zhang J, Lee WP, Roose-Girma M, Dixit VM. Kayagaki N, et al. Nature. 2011 Oct 16;479(7371):117-21. doi: 10.1038/nature10558. Nature. 2011. PMID: 22002608
DUBA: a deubiquitinase that regulates type I interferon production.
Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, O'Rourke KM, Eby M, Pietras E, Cheng G, Bazan JF, Zhang Z, Arnott D, Dixit VM. Kayagaki N, et al. Science. 2007 Dec 7;318(5856):1628-32. doi: 10.1126/science.1145918. Epub 2007 Nov 8. Science. 2007. PMID: 17991829
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.
Jones JW, Kayagaki N, Broz P, Henry T, Newton K, O'Rourke K, Chan S, Dong J, Qu Y, Roose-Girma M, Dixit VM, Monack DM. Jones JW, et al. Among authors: kayagaki n. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9771-6. doi: 10.1073/pnas.1003738107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457908 Free PMC article.
Phosphorylation-dependent activity of the deubiquitinase DUBA.
Huang OW, Ma X, Yin J, Flinders J, Maurer T, Kayagaki N, Phung Q, Bosanac I, Arnott D, Dixit VM, Hymowitz SG, Starovasnik MA, Cochran AG. Huang OW, et al. Among authors: kayagaki n. Nat Struct Mol Biol. 2012 Jan 15;19(2):171-5. doi: 10.1038/nsmb.2206. Nat Struct Mol Biol. 2012. PMID: 22245969
Phosphorylation of NLRC4 is critical for inflammasome activation.
Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour LL, Lamkanfi M, Louie S, Kayagaki N, Liu J, Kömüves L, Cupp JE, Arnott D, Monack D, Dixit VM. Qu Y, et al. Among authors: kayagaki n. Nature. 2012 Oct 25;490(7421):539-42. doi: 10.1038/nature11429. Epub 2012 Aug 12. Nature. 2012. PMID: 22885697
Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Kayagaki N, Wong MT, Stowe IB, Ramani SR, Gonzalez LC, Akashi-Takamura S, Miyake K, Zhang J, Lee WP, Muszyński A, Forsberg LS, Carlson RW, Dixit VM. Kayagaki N, et al. Science. 2013 Sep 13;341(6151):1246-9. doi: 10.1126/science.1240248. Epub 2013 Jul 25. Science. 2013. PMID: 23887873
106 results