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SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis.
Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, Lee CH, Evans RM. Nofsinger RR, et al. Among authors: leblanc m. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):20021-6. doi: 10.1073/pnas.0811012105. Epub 2008 Dec 9. Proc Natl Acad Sci U S A. 2008. PMID: 19066220 Free PMC article.
Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism.
Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM. Pei L, et al. Among authors: leblanc m. Cell Metab. 2015 Apr 7;21(4):628-36. doi: 10.1016/j.cmet.2015.03.004. Cell Metab. 2015. PMID: 25863252 Free PMC article.
Depletion of fat-resident Treg cells prevents age-associated insulin resistance.
Bapat SP, Myoung Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, LeBlanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y. Bapat SP, et al. Among authors: leblanc m. Nature. 2015 Dec 3;528(7580):137-41. doi: 10.1038/nature16151. Epub 2015 Nov 18. Nature. 2015. PMID: 26580014 Free PMC article.
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T. Shi Y, et al. Among authors: leblanc m. Nature. 2019 May;569(7754):131-135. doi: 10.1038/s41586-019-1130-6. Epub 2019 Apr 17. Nature. 2019. PMID: 30996350 Free PMC article.
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.
Ding N, Yu RT, Subramaniam N, Sherman MH, Wilson C, Rao R, Leblanc M, Coulter S, He M, Scott C, Lau SL, Atkins AR, Barish GD, Gunton JE, Liddle C, Downes M, Evans RM. Ding N, et al. Among authors: leblanc m. Cell. 2013 Apr 25;153(3):601-13. doi: 10.1016/j.cell.2013.03.028. Cell. 2013. PMID: 23622244 Free PMC article.
BRD4 is a novel therapeutic target for liver fibrosis.
Ding N, Hah N, Yu RT, Sherman MH, Benner C, Leblanc M, He M, Liddle C, Downes M, Evans RM. Ding N, et al. Among authors: leblanc m. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15713-8. doi: 10.1073/pnas.1522163112. Epub 2015 Dec 7. Proc Natl Acad Sci U S A. 2015. PMID: 26644586 Free PMC article.
FXR Regulates Intestinal Cancer Stem Cell Proliferation.
Fu T, Coulter S, Yoshihara E, Oh TG, Fang S, Cayabyab F, Zhu Q, Zhang T, Leblanc M, Liu S, He M, Waizenegger W, Gasser E, Schnabl B, Atkins AR, Yu RT, Knight R, Liddle C, Downes M, Evans RM. Fu T, et al. Among authors: leblanc m. Cell. 2019 Feb 21;176(5):1098-1112.e18. doi: 10.1016/j.cell.2019.01.036. Cell. 2019. PMID: 30794774 Free PMC article.
1,264 results