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Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.
Seimetz M, Parajuli N, Pichl A, Veit F, Kwapiszewska G, Weisel FC, Milger K, Egemnazarov B, Turowska A, Fuchs B, Nikam S, Roth M, Sydykov A, Medebach T, Klepetko W, Jaksch P, Dumitrascu R, Garn H, Voswinckel R, Kostin S, Seeger W, Schermuly RT, Grimminger F, Ghofrani HA, Weissmann N. Seimetz M, et al. Among authors: dumitrascu r. Cell. 2011 Oct 14;147(2):293-305. doi: 10.1016/j.cell.2011.08.035. Cell. 2011. PMID: 22000010 Free article.
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
Weissmann N, Dietrich A, Fuchs B, Kalwa H, Ay M, Dumitrascu R, Olschewski A, Storch U, Mederos y Schnitzler M, Ghofrani HA, Schermuly RT, Pinkenburg O, Seeger W, Grimminger F, Gudermann T. Weissmann N, et al. Among authors: dumitrascu r. Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19093-8. doi: 10.1073/pnas.0606728103. Epub 2006 Dec 1. Proc Natl Acad Sci U S A. 2006. PMID: 17142322 Free PMC article.
Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Schermuly RT, Pullamsetti SS, Kwapiszewska G, Dumitrascu R, Tian X, Weissmann N, Ghofrani HA, Kaulen C, Dunkern T, Schudt C, Voswinckel R, Zhou J, Samidurai A, Klepetko W, Paddenberg R, Kummer W, Seeger W, Grimminger F. Schermuly RT, et al. Among authors: dumitrascu r. Circulation. 2007 May 1;115(17):2331-9. doi: 10.1161/CIRCULATIONAHA.106.676809. Epub 2007 Apr 16. Circulation. 2007. PMID: 17438150
Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension.
Schermuly RT, Stasch JP, Pullamsetti SS, Middendorff R, Müller D, Schlüter KD, Dingendorf A, Hackemack S, Kolosionek E, Kaulen C, Dumitrascu R, Weissmann N, Mittendorf J, Klepetko W, Seeger W, Ghofrani HA, Grimminger F. Schermuly RT, et al. Among authors: dumitrascu r. Eur Respir J. 2008 Oct;32(4):881-91. doi: 10.1183/09031936.00114407. Epub 2008 Jun 11. Eur Respir J. 2008. PMID: 18550612 Free article.
39 results