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Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway.
Shi J, Guan J, Jiang B, Brenner DA, Del Monte F, Ward JE, Connors LH, Sawyer DB, Semigran MJ, Macgillivray TE, Seldin DC, Falk R, Liao R. Shi J, et al. Among authors: guan j. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4188-93. doi: 10.1073/pnas.0912263107. Epub 2010 Feb 11. Proc Natl Acad Sci U S A. 2010. PMID: 20150510 Free PMC article.
Current perspectives on cardiac amyloidosis.
Guan J, Mishra S, Falk RH, Liao R. Guan J, et al. Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H544-52. doi: 10.1152/ajpheart.00815.2011. Epub 2011 Nov 4. Am J Physiol Heart Circ Physiol. 2012. PMID: 22058156 Free PMC article. Review.
Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.
Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW Jr, Macrae CA, Liao R. Guan J, et al. Basic Res Cardiol. 2013 Sep;108(5):378. doi: 10.1007/s00395-013-0378-5. Epub 2013 Aug 28. Basic Res Cardiol. 2013. PMID: 23982491 Free PMC article.
A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure.
Jain M, Jakubowski A, Cui L, Shi J, Su L, Bauer M, Guan J, Lim CC, Naito Y, Thompson JS, Sam F, Ambrose C, Parr M, Crowell T, Lincecum JM, Wang MZ, Hsu YM, Zheng TS, Michaelson JS, Liao R, Burkly LC. Jain M, et al. Among authors: guan j. Circulation. 2009 Apr 21;119(15):2058-68. doi: 10.1161/CIRCULATIONAHA.108.837286. Epub 2009 Apr 6. Circulation. 2009. PMID: 19349318 Free PMC article.
Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease.
Tsukamoto K, Mani DR, Shi J, Zhang S, Haagensen DE, Otsuka F, Guan J, Smith JD, Weng W, Liao R, Kolodgie FD, Virmani R, Krieger M. Tsukamoto K, et al. Among authors: guan j. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17023-8. doi: 10.1073/pnas.1315986110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082102 Free PMC article.
4,773 results