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Page 1
Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.
Gotink KJ, Broxterman HJ, Labots M, de Haas RR, Dekker H, Honeywell RJ, Rudek MA, Beerepoot LV, Musters RJ, Jansen G, Griffioen AW, Assaraf YG, Pili R, Peters GJ, Verheul HM. Gotink KJ, et al. Among authors: musters rj. Clin Cancer Res. 2011 Dec 1;17(23):7337-46. doi: 10.1158/1078-0432.CCR-11-1667. Epub 2011 Oct 6. Clin Cancer Res. 2011. PMID: 21980135 Free PMC article.
Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function.
Van Der Steen N, Keller K, Dekker H, Porcelli L, Honeywell RJ, Van Meerloo J, Musters RJP, Kathmann I, Frampton AE, Liu DSK, Ruijtenbeek R, Rolfo C, Pauwels P, Giovannetti E, Peters GJ. Van Der Steen N, et al. Among authors: musters rjp. J Cell Physiol. 2020 Nov;235(11):8085-8097. doi: 10.1002/jcp.29463. Epub 2020 Jan 20. J Cell Physiol. 2020. PMID: 31960422 Free PMC article.
Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis.
Wojtuszkiewicz A, Schuurhuis GJ, Kessler FL, Piersma SR, Knol JC, Pham TV, Jansen G, Musters RJ, van Meerloo J, Assaraf YG, Kaspers GJ, Zweegman S, Cloos J, Jimenez CR. Wojtuszkiewicz A, et al. Among authors: musters rj. Mol Cell Proteomics. 2016 Apr;15(4):1281-98. doi: 10.1074/mcp.M115.052944. Epub 2016 Jan 22. Mol Cell Proteomics. 2016. PMID: 26801919 Free PMC article.
Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab.
Krejcik J, Frerichs KA, Nijhof IS, van Kessel B, van Velzen JF, Bloem AC, Broekmans MEC, Zweegman S, van Meerloo J, Musters RJP, Poddighe PJ, Groen RWJ, Chiu C, Plesner T, Lokhorst HM, Sasser AK, Mutis T, van de Donk NWCJ. Krejcik J, et al. Clin Cancer Res. 2017 Dec 15;23(24):7498-7511. doi: 10.1158/1078-0432.CCR-17-2027. Epub 2017 Oct 12. Clin Cancer Res. 2017. PMID: 29025767 Free PMC article. Clinical Trial.
Prophylactic and therapeutic activity of alkaline phosphatase in arthritic rats: single-agent effects of alkaline phosphatase and synergistic effects in combination with methotrexate.
Chandrupatla DMSH, Molthoff CFM, Ritsema WIGR, Vos R, Elshof E, Matsuyama T, Low PS, Musters RJP, Hammond A, Windhorst AD, Lammertsma AA, van der Laken CJ, Brands R, Jansen G. Chandrupatla DMSH, et al. Transl Res. 2018 Sep;199:24-38. doi: 10.1016/j.trsl.2018.04.001. Epub 2018 May 17. Transl Res. 2018. PMID: 29802817 Free article.
F8-IL10: A New Potential Antirheumatic Drug Evaluated by a PET-Guided Translational Approach.
Bruijnen STG, Chandrupatla DMSH, Giovanonni L, Neri D, Vugts DJ, Huisman MC, Hoekstra OS, Musters RJP, Lammertsma AA, van Dongen GAMS, Jansen G, Molthoff CFM, van der Laken CJ. Bruijnen STG, et al. Mol Pharm. 2019 Jan 7;16(1):273-281. doi: 10.1021/acs.molpharmaceut.8b00982. Epub 2018 Dec 24. Mol Pharm. 2019. PMID: 30550295 Free PMC article.
Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology.
Wiersma VI, van Ziel AM, Vazquez-Sanchez S, Nölle A, Berenjeno-Correa E, Bonaterra-Pastra A, Clavaguera F, Tolnay M, Musters RJP, van Weering JRT, Verhage M, Hoozemans JJM, Scheper W. Wiersma VI, et al. Acta Neuropathol. 2019 Dec;138(6):943-970. doi: 10.1007/s00401-019-02046-4. Epub 2019 Aug 27. Acta Neuropathol. 2019. PMID: 31456031 Free PMC article.
110 results