Patin D - Search Results

1

New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation.

Zidar N, Tomašić T, Šink R, Kovač A, Patin D, Blanot D, Contreras-Martel C, Dessen A, Premru MM, Zega A, Gobec S, Mašič LP, Kikelj D. Zidar N, et al. Among authors: patin d. Eur J Med Chem. 2011 Nov;46(11):5512-23. doi: 10.1016/j.ejmech.2011.09.017. Epub 2011 Sep 17. Eur J Med Chem. 2011. PMID: 21963114

2

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.

Tomašić T, Sink R, Zidar N, Fic A, Contreras-Martel C, Dessen A, Patin D, Blanot D, Müller-Premru M, Gobec S, Zega A, Kikelj D, Mašič LP. Tomašić T, et al. Among authors: patin d. ACS Med Chem Lett. 2012 Jun 27;3(8):626-30. doi: 10.1021/ml300047h. eCollection 2012 Aug 9. ACS Med Chem Lett. 2012. PMID: 24900523 Free PMC article.

3

Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases.

Hrast M, Rožman K, Ogris I, Škedelj V, Patin D, Sova M, Barreteau H, Gobec S, Grdadolnik SG, Zega A. Hrast M, et al. Among authors: patin d. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1010-1017. doi: 10.1080/14756366.2019.1608981. J Enzyme Inhib Med Chem. 2019. PMID: 31072165 Free PMC article.

4

Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.

Zidar N, Tomasić T, Sink R, Rupnik V, Kovac A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Müller Premru M, Zega A, Gobec S, Peterlin Masic L, Kikelj D. Zidar N, et al. Among authors: patin d. J Med Chem. 2010 Sep 23;53(18):6584-94. doi: 10.1021/jm100285g. J Med Chem. 2010. PMID: 20804196

5

MurD enzymes: some recent developments.

Šink R, Barreteau H, Patin D, Mengin-Lecreulx D, Gobec S, Blanot D. Šink R, et al. Among authors: patin d. Biomol Concepts. 2013 Dec;4(6):539-56. doi: 10.1515/bmc-2013-0024. Biomol Concepts. 2013. PMID: 25436755 Free article. Review.

6

Discovery of new MurA inhibitors using induced-fit simulation and docking.

Rožman K, Lešnik S, Brus B, Hrast M, Sova M, Patin D, Barreteau H, Konc J, Janežič D, Gobec S. Rožman K, et al. Among authors: patin d. Bioorg Med Chem Lett. 2017 Feb 15;27(4):944-949. doi: 10.1016/j.bmcl.2016.12.082. Epub 2016 Dec 31. Bioorg Med Chem Lett. 2017. PMID: 28077258

7

Synthesis and structure-activity relationship study of novel quinazolinone-based inhibitors of MurA.

Hrast M, Rožman K, Jukič M, Patin D, Gobec S, Sova M. Hrast M, et al. Among authors: patin d. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3529-3533. doi: 10.1016/j.bmcl.2017.05.064. Epub 2017 May 22. Bioorg Med Chem Lett. 2017. PMID: 28579123

8

In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB.

Hrast M, Jukič M, Patin D, Tod J, Dowson CG, Roper DI, Barreteau H, Gobec S. Hrast M, et al. Among authors: patin d. Chem Biol Drug Des. 2018 Jun;91(6):1101-1112. doi: 10.1111/cbdd.13172. Epub 2018 Feb 12. Chem Biol Drug Des. 2018. PMID: 29363274

9

Unusual substrate specificity of the peptidoglycan MurE ligase from Erysipelothrix rhusiopathiae.

Patin D, Turk S, Barreteau H, Mainardi JL, Arthur M, Gobec S, Mengin-Lecreulx D, Blanot D. Patin D, et al. Biochimie. 2016 Feb;121:209-18. doi: 10.1016/j.biochi.2015.12.006. Epub 2015 Dec 14. Biochimie. 2016. PMID: 26700151

10

Synthetic tripeptides as alternate substrates of murein peptide ligase (Mpl).

Hervé M, Kovač A, Cardoso C, Patin D, Brus B, Barreteau H, Mengin-Lecreulx D, Gobec S, Blanot D. Hervé M, et al. Among authors: patin d. Biochimie. 2013 Jun;95(6):1120-6. doi: 10.1016/j.biochi.2012.12.011. Epub 2012 Dec 25. Biochimie. 2013. PMID: 23270797

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