A 'Good' muscle in a 'Bad' environment: the importance of airway smooth muscle force adaptation to airway hyperresponsiveness.
Bossé Y, Chapman DG, Paré PD, King GG, Salome CM.
Bossé Y, et al.
Respir Physiol Neurobiol. 2011 Dec 15;179(2-3):269-75. doi: 10.1016/j.resp.2011.09.003. Epub 2011 Sep 14.
Respir Physiol Neurobiol. 2011.
PMID: 21939788
Recent ex vivo data has suggested a novel mechanism by which inflammation may lead to AHR, in which increased basal ASM-tone, due to the presence of spasmogens in the airways, may "strengthen" the ASM and ultimately lead to exaggerated airway narrowing. This phenomenon was termed …
Recent ex vivo data has suggested a novel mechanism by which inflammation may lead to AHR, in which increased basal ASM-tone, due to the pre …