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Cognitive deficits develop 1month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge.
Muccigrosso MM, Ford J, Benner B, Moussa D, Burnsides C, Fenn AM, Popovich PG, Lifshitz J, Walker FR, Eiferman DS, Godbout JP. Muccigrosso MM, et al. Among authors: fenn am. Brain Behav Immun. 2016 May;54:95-109. doi: 10.1016/j.bbi.2016.01.009. Epub 2016 Jan 14. Brain Behav Immun. 2016. PMID: 26774527 Free PMC article.
Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice.
Wohleb ES, Fenn AM, Pacenta AM, Powell ND, Sheridan JF, Godbout JP. Wohleb ES, et al. Among authors: fenn am. Psychoneuroendocrinology. 2012 Sep;37(9):1491-505. doi: 10.1016/j.psyneuen.2012.02.003. Epub 2012 Mar 2. Psychoneuroendocrinology. 2012. PMID: 22386198 Free PMC article.
24 results