Kline CL - Search Results

1

The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU.

Kline CL, Irby RB. Kline CL, et al. Apoptosis. 2011 Dec;16(12):1285-94. doi: 10.1007/s10495-011-0648-3. Apoptosis. 2011. PMID: 21910008

2

Src kinase induces tumor formation in the c-SRC C57BL/6 mouse.

Kline CL, Jackson R, Engelman R, Pledger WJ, Yeatman TJ, Irby RB. Kline CL, et al. Int J Cancer. 2008 Jun 15;122(12):2665-73. doi: 10.1002/ijc.23445. Int J Cancer. 2008. PMID: 18351644 Free article.

3

Src activity alters alpha3 integrin expression in colon tumor cells.

Kline CL, Olson TL, Irby RB. Kline CL, et al. Clin Exp Metastasis. 2009;26(2):77-87. doi: 10.1007/s10585-008-9215-x. Epub 2008 Oct 7. Clin Exp Metastasis. 2009. PMID: 18839319

4

Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.

Wang BD, Kline CL, Pastor DM, Olson TL, Frank B, Luu T, Sharma AK, Robertson G, Weirauch MT, Patierno SR, Stuart JM, Irby RB, Lee NH. Wang BD, et al. Among authors: kline cl. Mol Cancer. 2010 Apr 30;9:98. doi: 10.1186/1476-4598-9-98. Mol Cancer. 2010. PMID: 20433755 Free PMC article.

5

Glucosamine-induced phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 is mediated by the protein kinase R-like endoplasmic-reticulum associated kinase.

Kline CL, Schrufer TL, Jefferson LS, Kimball SR. Kline CL, et al. Int J Biochem Cell Biol. 2006;38(5-6):1004-14. doi: 10.1016/j.biocel.2005.10.015. Epub 2005 Nov 16. Int J Biochem Cell Biol. 2006. PMID: 16324875

6

ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases.

Kline CL, Van den Heuvel AP, Allen JE, Prabhu VV, Dicker DT, El-Deiry WS. Kline CL, et al. Sci Signal. 2016 Feb 16;9(415):ra18. doi: 10.1126/scisignal.aac4374. Sci Signal. 2016. PMID: 26884600 Free PMC article.

7

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.

Zhang S, Zhou L, Hong B, van den Heuvel AP, Prabhu VV, Warfel NA, Kline CL, Dicker DT, Kopelovich L, El-Deiry WS. Zhang S, et al. Among authors: kline cl. Cancer Res. 2015 Sep 15;75(18):3842-52. doi: 10.1158/0008-5472.CAN-13-1079. Epub 2015 Aug 20. Cancer Res. 2015. PMID: 26294215 Free PMC article.

8

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.

Prabhu VV, Lulla AR, Madhukar NS, Ralff MD, Zhao D, Kline CLB, Van den Heuvel APJ, Lev A, Garnett MJ, McDermott U, Benes CH, Batchelor TT, Chi AS, Elemento O, Allen JE, El-Deiry WS. Prabhu VV, et al. Among authors: kline clb. PLoS One. 2017 Aug 2;12(8):e0180541. doi: 10.1371/journal.pone.0180541. eCollection 2017. PLoS One. 2017. PMID: 28767654 Free PMC article.

9

Personalizing colon cancer therapeutics: targeting old and new mechanisms of action.

Kline CL, El-Deiry WS. Kline CL, et al. Pharmaceuticals (Basel). 2013 Aug 21;6(8):988-1038. doi: 10.3390/ph6080988. Pharmaceuticals (Basel). 2013. PMID: 24276379 Free PMC article.

10

Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.

Prabhu VV, Talekar MK, Lulla AR, Kline CLB, Zhou L, Hall J, Van den Heuvel APJ, Dicker DT, Babar J, Grupp SA, Garnett MJ, McDermott U, Benes CH, Pu JJ, Claxton DF, Khan N, Oster W, Allen JE, El-Deiry WS. Prabhu VV, et al. Among authors: kline clb. Cell Cycle. 2018;17(4):468-478. doi: 10.1080/15384101.2017.1403689. Epub 2018 Feb 19. Cell Cycle. 2018. PMID: 29157092 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

48 results

Search Page