Irby RB - Search Results

1

The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU.

Kline CL, Irby RB. Kline CL, et al. Among authors: irby rb. Apoptosis. 2011 Dec;16(12):1285-94. doi: 10.1007/s10495-011-0648-3. Apoptosis. 2011. PMID: 21910008

2

Src kinase induces tumor formation in the c-SRC C57BL/6 mouse.

Kline CL, Jackson R, Engelman R, Pledger WJ, Yeatman TJ, Irby RB. Kline CL, et al. Among authors: irby rb. Int J Cancer. 2008 Jun 15;122(12):2665-73. doi: 10.1002/ijc.23445. Int J Cancer. 2008. PMID: 18351644 Free article.

3

Src activity alters alpha3 integrin expression in colon tumor cells.

Kline CL, Olson TL, Irby RB. Kline CL, et al. Among authors: irby rb. Clin Exp Metastasis. 2009;26(2):77-87. doi: 10.1007/s10585-008-9215-x. Epub 2008 Oct 7. Clin Exp Metastasis. 2009. PMID: 18839319

4

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU.

Kline CL, Shanmugavelandy SS, Kester M, Irby RB. Kline CL, et al. Among authors: irby rb. Cancer Biol Ther. 2009 Oct;8(19):1831-7. doi: 10.4161/cbt.8.19.9592. Cancer Biol Ther. 2009. PMID: 19729995

5

The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.

Sharma AK, Kline CL, Berg A, Amin S, Irby RB. Sharma AK, et al. Among authors: irby rb. Clin Cancer Res. 2011 Jul 1;17(13):4474-83. doi: 10.1158/1078-0432.CCR-10-2370. Epub 2011 May 9. Clin Cancer Res. 2011. PMID: 21555373 Free PMC article.

6

Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.

Wang BD, Kline CL, Pastor DM, Olson TL, Frank B, Luu T, Sharma AK, Robertson G, Weirauch MT, Patierno SR, Stuart JM, Irby RB, Lee NH. Wang BD, et al. Among authors: irby rb. Mol Cancer. 2010 Apr 30;9:98. doi: 10.1186/1476-4598-9-98. Mol Cancer. 2010. PMID: 20433755 Free PMC article.

7

Primary cell lines: false representation or model system? a comparison of four human colorectal tumors and their coordinately established cell lines.

Pastor DM, Poritz LS, Olson TL, Kline CL, Harris LR, Koltun WA, Chinchilli VM, Irby RB. Pastor DM, et al. Among authors: irby rb. Int J Clin Exp Med. 2010 Feb 22;3(1):69-83. Int J Clin Exp Med. 2010. PMID: 20369042 Free PMC article.

8

TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells.

Nguyen JQ, Irby RB. Nguyen JQ, et al. Among authors: irby rb. Cancer Biol Ther. 2017 Jan 2;18(1):16-25. doi: 10.1080/15384047.2016.1252880. Epub 2016 Nov 10. Cancer Biol Ther. 2017. PMID: 27830973 Free PMC article.

9

The Akt inhibitor ISC-4 synergizes with cetuximab in 5-FU-resistant colon cancer.

Allen JE, Gallant JN, Dicker DT, Amin S, Irby RB, Sharma AK, El-Deiry WS. Allen JE, et al. Among authors: irby rb. PLoS One. 2013;8(3):e59380. doi: 10.1371/journal.pone.0059380. Epub 2013 Mar 12. PLoS One. 2013. PMID: 23555026 Free PMC article.

10

Par-4 as a potential target for cancer therapy.

Irby RB, Kline CL. Irby RB, et al. Expert Opin Ther Targets. 2013 Jan;17(1):77-87. doi: 10.1517/14728222.2013.731047. Epub 2012 Oct 15. Expert Opin Ther Targets. 2013. PMID: 23062118 Review.

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