Aránega A - Search Results

1

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells.

García MA, Carrasco E, Aguilera M, Alvarez P, Rivas C, Campos JM, Prados JC, Calleja MA, Esteban M, Marchal JA, Aránega A. García MA, et al. Among authors: aranega a. PLoS One. 2011;6(8):e23887. doi: 10.1371/journal.pone.0023887. Epub 2011 Aug 24. PLoS One. 2011. PMID: 21887339 Free PMC article.

2

Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives.

Marchal JA, Boulaiz H, Suárez I, Saniger E, Campos J, Carrillo E, Prados J, Gallo MA, Espinosa A, Aránega A. Marchal JA, et al. Among authors: aranega a. Invest New Drugs. 2004 Nov;22(4):379-89. doi: 10.1023/B:DRUG.0000036680.52016.5f. Invest New Drugs. 2004. PMID: 15292708

3

Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells.

Marchal JA, Rodríguez-Serrano F, Caba O, Aránega A, Gallo MA, Espinosa A, Campos JM. Marchal JA, et al. Among authors: aranega a. ChemMedChem. 2007 Dec;2(12):1814-21. doi: 10.1002/cmdc.200700142. ChemMedChem. 2007. PMID: 17969215

4

E phage gene transfection enhances sensitivity of lung and colon cancer cells to chemotherapeutic agents.

Rama AR, Prados J, Melguizo C, Ortiz R, Alvarez PJ, Rodríguez-Serrano F, Hita F, Ramos JL, Burgos M, Aranega A. Rama AR, et al. Among authors: aranega a. Int J Oncol. 2010 Dec;37(6):1503-14. doi: 10.3892/ijo_00000803. Int J Oncol. 2010. PMID: 21042719

5

E phage gene transfection associated to chemotherapeutic agents increases apoptosis in lung and colon cancer cells.

Rama AR, Prados J, Melguizo C, Alvarez PJ, Ortiz R, Madeddu R, Aranega A. Rama AR, et al. Among authors: aranega a. Bioeng Bugs. 2011 May-Jun;2(3):163-7. doi: 10.4161/bbug.2.3.15533. Bioeng Bugs. 2011. PMID: 21747234

6

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

Kimatrai M, Conejo-García A, Ramírez A, Andreolli E, Da Silveira-Gomes A, García MA, Aránega A, Marchal JA, Campos JM. Kimatrai M, et al. Among authors: aranega a. ChemMedChem. 2011 Oct 4;6(10):1854-9. doi: 10.1002/cmdc.201100276. Epub 2011 Jul 27. ChemMedChem. 2011. PMID: 21796794

7

gef gene expression in MCF-7 breast cancer cells is associated with a better prognosis and induction of apoptosis by p53-mediated signaling pathway.

Boulaiz H, Alvarez PJ, Prados J, Marchal J, Melguizo C, Carrillo E, Peran M, Rodríguez F, Ramírez A, Ortíz R, Aránega A. Boulaiz H, et al. Among authors: aranega a. Int J Mol Sci. 2011;12(11):7445-58. doi: 10.3390/ijms12117445. Epub 2011 Oct 31. Int J Mol Sci. 2011. PMID: 22174609 Free PMC article.

8

5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer.

Ortiz R, Prados J, Melguizo C, Arias JL, Ruiz MA, Alvarez PJ, Caba O, Luque R, Segura A, Aránega A. Ortiz R, et al. Among authors: aranega a. Int J Nanomedicine. 2012;7:95-107. doi: 10.2147/IJN.S26401. Epub 2012 Jan 9. Int J Nanomedicine. 2012. PMID: 22275826 Free PMC article.

9

5-Fluorouracil derivatives: a patent review.

Álvarez P, Marchal JA, Boulaiz H, Carrillo E, Vélez C, Rodríguez-Serrano F, Melguizo C, Prados J, Madeddu R, Aranega A. Álvarez P, et al. Among authors: aranega a. Expert Opin Ther Pat. 2012 Feb;22(2):107-23. doi: 10.1517/13543776.2012.661413. Epub 2012 Feb 14. Expert Opin Ther Pat. 2012. PMID: 22329541 Review.

10

Doxorubicin-loaded nanoparticles: new advances in breast cancer therapy.

Prados J, Melguizo C, Ortiz R, Vélez C, Alvarez PJ, Arias JL, Ruíz MA, Gallardo V, Aranega A. Prados J, et al. Among authors: aranega a. Anticancer Agents Med Chem. 2012 Nov;12(9):1058-70. doi: 10.2174/187152012803529646. Anticancer Agents Med Chem. 2012. PMID: 22339066 Review.

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