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General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL.
Fazi C, Scarfò L, Pecciarini L, Cottini F, Dagklis A, Janus A, Talarico A, Scielzo C, Sala C, Toniolo D, Caligaris-Cappio F, Ghia P. Fazi C, et al. Among authors: dagklis a. Blood. 2011 Dec 15;118(25):6618-25. doi: 10.1182/blood-2011-05-357251. Epub 2011 Aug 29. Blood. 2011. PMID: 21876118 Free article.
HS1 has a central role in the trafficking and homing of leukemic B cells.
Scielzo C, Bertilaccio MT, Simonetti G, Dagklis A, ten Hacken E, Fazi C, Muzio M, Caiolfa V, Kitamura D, Restuccia U, Bachi A, Rocchi M, Ponzoni M, Ghia P, Caligaris-Cappio F. Scielzo C, et al. Among authors: dagklis a. Blood. 2010 Nov 4;116(18):3537-46. doi: 10.1182/blood-2009-12-258814. Epub 2010 Jun 8. Blood. 2010. PMID: 20530793 Free article.
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.
Bertilaccio MT, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, Mantovani A, Ponzoni M, Ghia P, Garlanda C, Caligaris-Cappio F, Muzio M. Bertilaccio MT, et al. Among authors: dagklis a. Blood. 2011 Jul 21;118(3):660-9. doi: 10.1182/blood-2011-01-329870. Epub 2011 Jun 7. Blood. 2011. PMID: 21652674 Free article.
Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.
Vardi A, Dagklis A, Scarfò L, Jelinek D, Newton D, Bennett F, Almeida J, Rodriguez-Caballero A, Allgood S, Lanasa M, Cortelezzi A, Orlandi E, Veronese S, Montillo M, Rawstron A, Shanafelt T, Orfao A, Stamatopoulos K, Ghia P. Vardi A, et al. Among authors: dagklis a. Blood. 2013 May 30;121(22):4521-8. doi: 10.1182/blood-2012-12-471698. Epub 2013 Apr 17. Blood. 2013. PMID: 23596047 Free article.
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.
Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P. Simonetti G, et al. Among authors: dagklis a. Haematologica. 2014 Aug;99(8):1356-64. doi: 10.3324/haematol.2013.100230. Epub 2014 May 23. Haematologica. 2014. PMID: 24859880 Free PMC article.
25 results