Eisenreich W - Search Results

1

Reverse fosmidomycin derivatives against the antimalarial drug target IspC (Dxr).

Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Pein MK, Gräwert T, Kaiser J, Bacher A, Eisenreich W, Illarionov B, Fischer M, Maes L, Groll M, Kurz T. Behrendt CT, et al. Among authors: eisenreich w. J Med Chem. 2011 Oct 13;54(19):6796-802. doi: 10.1021/jm200694q. Epub 2011 Sep 13. J Med Chem. 2011. PMID: 21866890

2

Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development.

Steinbacher S, Kaiser J, Eisenreich W, Huber R, Bacher A, Rohdich F. Steinbacher S, et al. Among authors: eisenreich w. J Biol Chem. 2003 May 16;278(20):18401-7. doi: 10.1074/jbc.M300993200. Epub 2003 Mar 5. J Biol Chem. 2003. PMID: 12621040 Free article.

3

Nonmevalonate terpene biosynthesis enzymes as antiinfective drug targets: substrate synthesis and high-throughput screening methods.

Illarionova V, Kaiser J, Ostrozhenkova E, Bacher A, Fischer M, Eisenreich W, Rohdich F. Illarionova V, et al. Among authors: eisenreich w. J Org Chem. 2006 Nov 10;71(23):8824-34. doi: 10.1021/jo061466o. J Org Chem. 2006. PMID: 17081012

4

Synthesis and antiplasmodial activity of highly active reverse analogues of the antimalarial drug candidate fosmidomycin.

Behrendt CT, Kunfermann A, Illarionova V, Matheeussen A, Gräwert T, Groll M, Rohdich F, Bacher A, Eisenreich W, Fischer M, Maes L, Kurz T. Behrendt CT, et al. Among authors: eisenreich w. ChemMedChem. 2010 Oct 4;5(10):1673-6. doi: 10.1002/cmdc.201000276. ChemMedChem. 2010. PMID: 20718073 No abstract available.

5

IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters.

Kunfermann A, Lienau C, Illarionov B, Held J, Gräwert T, Behrendt CT, Werner P, Hähn S, Eisenreich W, Riederer U, Mordmüller B, Bacher A, Fischer M, Groll M, Kurz T. Kunfermann A, et al. Among authors: eisenreich w. J Med Chem. 2013 Oct 24;56(20):8151-62. doi: 10.1021/jm4012559. Epub 2013 Oct 7. J Med Chem. 2013. PMID: 24032981

6

Biosynthesis of hyperforin in Hypericum perforatum.

Adam P, Arigoni D, Bacher A, Eisenreich W. Adam P, et al. Among authors: eisenreich w. J Med Chem. 2002 Oct 10;45(21):4786-93. doi: 10.1021/jm0209782. J Med Chem. 2002. PMID: 12361406

7

Biosynthetic origin of a branched chain analogue of the lipase inhibitor, lipstatin.

Eisenreich W, Kupfer E, Stohler P, Weber W, Bacher A. Eisenreich W, et al. J Med Chem. 2003 Sep 11;46(19):4209-12. doi: 10.1021/jm030780x. J Med Chem. 2003. PMID: 12954074

8

Rapid preparation of isotopolog libraries by in vivo transformation of 1)C-glucose. Studies on 6,7-dimethyl-8-ribityllumazine, a biosynthetic precursor of vitamin B2.

Illarionov B, Fischer M, Lee CY, Bacher A, Eisenreich W. Illarionov B, et al. Among authors: eisenreich w. J Org Chem. 2004 Aug 20;69(17):5588-94. doi: 10.1021/jo0493222. J Org Chem. 2004. PMID: 15307727

9

Perspectives in anti-infective drug design. The late steps in the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate and dimethylallyl diphosphate.

Rohdich F, Bacher A, Eisenreich W. Rohdich F, et al. Among authors: eisenreich w. Bioorg Chem. 2004 Oct;32(5):292-308. doi: 10.1016/j.bioorg.2004.05.012. Bioorg Chem. 2004. PMID: 15381396 Review.

10

Biosynthesis of vitamin B2: diastereomeric reaction intermediates of archaeal and non-archaeal riboflavin synthases.

Illarionov B, Eisenreich W, Schramek N, Bacher A, Fischer M. Illarionov B, et al. Among authors: eisenreich w. J Biol Chem. 2005 Aug 5;280(31):28541-6. doi: 10.1074/jbc.M503093200. Epub 2005 Jun 8. J Biol Chem. 2005. PMID: 15944152 Free article.

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