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New target for inhibition of bacterial RNA polymerase: 'switch region'.
Srivastava A, Talaue M, Liu S, Degen D, Ebright RY, Sineva E, Chakraborty A, Druzhinin SY, Chatterjee S, Mukhopadhyay J, Ebright YW, Zozula A, Shen J, Sengupta S, Niedfeldt RR, Xin C, Kaneko T, Irschik H, Jansen R, Donadio S, Connell N, Ebright RH. Srivastava A, et al. Among authors: degen d. Curr Opin Microbiol. 2011 Oct;14(5):532-43. doi: 10.1016/j.mib.2011.07.030. Epub 2011 Aug 19. Curr Opin Microbiol. 2011. PMID: 21862392 Free PMC article. Review.
Transcription inhibition by the depsipeptide antibiotic salinamide A.
Degen D, Feng Y, Zhang Y, Ebright KY, Ebright YW, Gigliotti M, Vahedian-Movahed H, Mandal S, Talaue M, Connell N, Arnold E, Fenical W, Ebright RH. Degen D, et al. Elife. 2014 Apr 30;3:e02451. doi: 10.7554/eLife.02451. Elife. 2014. PMID: 24843001 Free PMC article.
Synthesis and evaluation of novel analogues of ripostatins.
Tang W, Liu S, Degen D, Ebright RH, Prusov EV. Tang W, et al. Among authors: degen d. Chemistry. 2014 Sep 15;20(38):12310-9. doi: 10.1002/chem.201403176. Epub 2014 Aug 11. Chemistry. 2014. PMID: 25112727 Free PMC article.
Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Lin W, Mandal S, Degen D, Liu Y, Ebright YW, Li S, Feng Y, Zhang Y, Mandal S, Jiang Y, Liu S, Gigliotti M, Talaue M, Connell N, Das K, Arnold E, Ebright RH. Lin W, et al. Among authors: degen d. Mol Cell. 2017 Apr 20;66(2):169-179.e8. doi: 10.1016/j.molcel.2017.03.001. Epub 2017 Apr 6. Mol Cell. 2017. PMID: 28392175 Free PMC article.
Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Maffioli SI, Zhang Y, Degen D, Carzaniga T, Del Gatto G, Serina S, Monciardini P, Mazzetti C, Guglierame P, Candiani G, Chiriac AI, Facchetti G, Kaltofen P, Sahl HG, Dehò G, Donadio S, Ebright RH. Maffioli SI, et al. Among authors: degen d. Cell. 2017 Jun 15;169(7):1240-1248.e23. doi: 10.1016/j.cell.2017.05.042. Cell. 2017. PMID: 28622509 Free PMC article.
41 results