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S100A1 genetically targeted therapy reverses dysfunction of human failing cardiomyocytes.
Brinks H, Rohde D, Voelkers M, Qiu G, Pleger ST, Herzog N, Rabinowitz J, Ruhparwar A, Silvestry S, Lerchenmüller C, Mather PJ, Eckhart AD, Katus HA, Carrel T, Koch WJ, Most P. Brinks H, et al. J Am Coll Cardiol. 2011 Aug 23;58(9):966-73. doi: 10.1016/j.jacc.2011.03.054. J Am Coll Cardiol. 2011. PMID: 21851887 Free PMC article.
The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.
Völkers M, Weidenhammer C, Herzog N, Qiu G, Spaich K, Wegner FV, Peppel K, Müller OJ, Schinkel S, Rabinowitz JE, Hippe HJ, Brinks H, Katus HA, Koch WJ, Eckhart AD, Friedrich O, Most P. Völkers M, et al. Among authors: brinks h. Circ Res. 2011 Jan 7;108(1):27-39. doi: 10.1161/CIRCRESAHA.110.225201. Epub 2010 Nov 24. Circ Res. 2011. PMID: 21106943 Free PMC article.
Heart failure gene therapy: the path to clinical practice.
Pleger ST, Brinks H, Ritterhoff J, Raake P, Koch WJ, Katus HA, Most P. Pleger ST, et al. Among authors: brinks h. Circ Res. 2013 Aug 30;113(6):792-809. doi: 10.1161/CIRCRESAHA.113.300269. Circ Res. 2013. PMID: 23989720 Review.
Clinical outcomes of patients with severe aortic stenosis at increased surgical risk according to treatment modality.
Wenaweser P, Pilgrim T, Kadner A, Huber C, Stortecky S, Buellesfeld L, Khattab AA, Meuli F, Roth N, Eberle B, Erdös G, Brinks H, Kalesan B, Meier B, Jüni P, Carrel T, Windecker S. Wenaweser P, et al. Among authors: brinks h. J Am Coll Cardiol. 2011 Nov 15;58(21):2151-62. doi: 10.1016/j.jacc.2011.05.063. J Am Coll Cardiol. 2011. PMID: 22078420 Free article. Clinical Trial.
Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.
Raake PW, Zhang X, Vinge LE, Brinks H, Gao E, Jaleel N, Li Y, Tang M, Most P, Dorn GW 2nd, Houser SR, Katus HA, Chen X, Koch WJ. Raake PW, et al. Among authors: brinks h. Circulation. 2012 May 1;125(17):2108-18. doi: 10.1161/CIRCULATIONAHA.111.044255. Epub 2012 Apr 10. Circulation. 2012. PMID: 22496128 Free PMC article.
30 results