Ron D - Search Results

1

Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response.

Fribley AM, Cruz PG, Miller JR, Callaghan MU, Cai P, Narula N, Neubig RR, Showalter HD, Larsen SD, Kirchhoff PD, Larsen MJ, Burr DA, Schultz PJ, Jacobs RR, Tamayo-Castillo G, Ron D, Sherman DH, Kaufman RJ. Fribley AM, et al. Among authors: ron d. J Biomol Screen. 2011 Sep;16(8):825-35. doi: 10.1177/1087057111414893. Epub 2011 Aug 15. J Biomol Screen. 2011. PMID: 21844328 Free PMC article.

2

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2.

Lu PD, Jousse C, Marciniak SJ, Zhang Y, Novoa I, Scheuner D, Kaufman RJ, Ron D, Harding HP. Lu PD, et al. Among authors: ron d. EMBO J. 2004 Jan 14;23(1):169-79. doi: 10.1038/sj.emboj.7600030. Epub 2004 Jan 8. EMBO J. 2004. PMID: 14713949 Free PMC article.

3

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.

Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, Harding HP, Ron D. Deng J, et al. Among authors: ron d. Mol Cell Biol. 2004 Dec;24(23):10161-8. doi: 10.1128/MCB.24.23.10161-10168.2004. Mol Cell Biol. 2004. PMID: 15542827 Free PMC article.

4

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth.

Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N, Harding H, Novoa I, Varia M, Raleigh J, Scheuner D, Kaufman RJ, Bell J, Ron D, Wouters BG, Koumenis C. Bi M, et al. Among authors: ron d. EMBO J. 2005 Oct 5;24(19):3470-81. doi: 10.1038/sj.emboj.7600777. Epub 2005 Sep 8. EMBO J. 2005. PMID: 16148948 Free PMC article.

5

Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression.

Harding HP, Zhang Y, Khersonsky S, Marciniak S, Scheuner D, Kaufman RJ, Javitt N, Chang YT, Ron D. Harding HP, et al. Among authors: ron d. Cell Metab. 2005 Dec;2(6):361-71. doi: 10.1016/j.cmet.2005.11.005. Cell Metab. 2005. PMID: 16330322 Free PMC article.

6

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux.

Shang J, Gao N, Kaufman RJ, Ron D, Harding HP, Lehrman MA. Shang J, et al. Among authors: ron d. J Cell Biol. 2007 Feb 26;176(5):605-16. doi: 10.1083/jcb.200607007. J Cell Biol. 2007. PMID: 17325203 Free PMC article.

7

Novel function of PERK as a mediator of force-induced apoptosis.

Mak BC, Wang Q, Laschinger C, Lee W, Ron D, Harding HP, Kaufman RJ, Scheuner D, Austin RC, McCulloch CA. Mak BC, et al. Among authors: ron d. J Biol Chem. 2008 Aug 22;283(34):23462-72. doi: 10.1074/jbc.M803194200. Epub 2008 Jun 11. J Biol Chem. 2008. PMID: 18550523 Free PMC article.

8

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.

Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ. Song B, et al. Among authors: ron d. J Clin Invest. 2008 Oct;118(10):3378-89. doi: 10.1172/JCI34587. J Clin Invest. 2008. PMID: 18776938 Free PMC article.

9

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development.

Harding HP, Zhang Y, Scheuner D, Chen JJ, Kaufman RJ, Ron D. Harding HP, et al. Among authors: ron d. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1832-7. doi: 10.1073/pnas.0809632106. Epub 2009 Jan 30. Proc Natl Acad Sci U S A. 2009. PMID: 19181853 Free PMC article.

10

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.

Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, Yuan J. Boyce M, et al. Among authors: ron d. Science. 2005 Feb 11;307(5711):935-9. doi: 10.1126/science.1101902. Science. 2005. PMID: 15705855

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