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Reducing plasma membrane sphingomyelin increases insulin sensitivity.
Li Z, Zhang H, Liu J, Liang CP, Li Y, Li Y, Teitelman G, Beyer T, Bui HH, Peake DA, Zhang Y, Sanders PE, Kuo MS, Park TS, Cao G, Jiang XC. Li Z, et al. Among authors: park ts. Mol Cell Biol. 2011 Oct;31(20):4205-18. doi: 10.1128/MCB.05893-11. Epub 2011 Aug 15. Mol Cell Biol. 2011. PMID: 21844222 Free PMC article.
Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.
Li Z, Park TS, Li Y, Pan X, Iqbal J, Lu D, Tang W, Yu L, Goldberg IJ, Hussain MM, Jiang XC. Li Z, et al. Among authors: park ts. Biochim Biophys Acta. 2009 Apr;1791(4):297-306. doi: 10.1016/j.bbalip.2009.01.010. Epub 2009 Jan 29. Biochim Biophys Acta. 2009. PMID: 19416652 Free PMC article.
Ceramide is a cardiotoxin in lipotoxic cardiomyopathy.
Park TS, Hu Y, Noh HL, Drosatos K, Okajima K, Buchanan J, Tuinei J, Homma S, Jiang XC, Abel ED, Goldberg IJ. Park TS, et al. J Lipid Res. 2008 Oct;49(10):2101-12. doi: 10.1194/jlr.M800147-JLR200. Epub 2008 May 30. J Lipid Res. 2008. PMID: 18515784 Free PMC article.
Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction.
Lee SY, Kim JR, Hu Y, Khan R, Kim SJ, Bharadwaj KG, Davidson MM, Choi CS, Shin KO, Lee YM, Park WJ, Park IS, Jiang XC, Goldberg IJ, Park TS. Lee SY, et al. Among authors: park ts, park is, park wj. J Biol Chem. 2012 May 25;287(22):18429-39. doi: 10.1074/jbc.M111.296947. Epub 2012 Apr 9. J Biol Chem. 2012. PMID: 22493506 Free PMC article.
1,057 results