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Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells.
J Immunol. 2011 Sep 15;187(6):3438-47. doi: 10.4049/jimmunol.1101189. Epub 2011 Aug 12.
J Immunol. 2011.
PMID: 21841127
Penetration of antibody-opsonized cells by the membrane attack complex of complement promotes Ca(2+) influx and induces streamers.
Beum PV, Lindorfer MA, Peek EM, Stukenberg PT, de Weers M, Beurskens FJ, Parren PW, van de Winkel JG, Taylor RP.
Beum PV, et al. Among authors: peek em.
Eur J Immunol. 2011 Aug;41(8):2436-46. doi: 10.1002/eji.201041204. Epub 2011 Jul 4.
Eur J Immunol. 2011.
PMID: 21674476
Free article.
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A novel approach to preventing the hemolysis of paroxysmal nocturnal hemoglobinuria: both complement-mediated cytolysis and C3 deposition are blocked by a monoclonal antibody specific for the alternative pathway of complement.
Lindorfer MA, Pawluczkowycz AW, Peek EM, Hickman K, Taylor RP, Parker CJ.
Lindorfer MA, et al. Among authors: peek em.
Blood. 2010 Mar 18;115(11):2283-91. doi: 10.1182/blood-2009-09-244285. Epub 2010 Jan 12.
Blood. 2010.
PMID: 20068220
Free article.
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Loss of MyD88 leads to more aggressive TRAMP prostate cancer and influences tumor infiltrating lymphocytes.
Peek EM, Song W, Zhang H, Huang J, Chin AI.
Peek EM, et al.
Prostate. 2015 Apr 1;75(5):463-73. doi: 10.1002/pros.22932. Epub 2015 Jan 16.
Prostate. 2015.
PMID: 25597486
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Synergy of Histone-Deacetylase Inhibitor AR-42 with Cisplatin in Bladder Cancer.
Li DR, Zhang H, Peek E, Wang S, Du L, Li G, Chin AI.
Li DR, et al.
J Urol. 2015 Aug;194(2):547-55. doi: 10.1016/j.juro.2015.02.2918. Epub 2015 Mar 3.
J Urol. 2015.
PMID: 25748177
Free PMC article.
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Stromal modulation of bladder cancer-initiating cells in a subcutaneous tumor model.
Peek EM, Li DR, Zhang H, Kim HP, Zhang B, Garraway IP, Chin AI.
Peek EM, et al.
Am J Cancer Res. 2012;2(6):745-51. Epub 2012 Nov 20.
Am J Cancer Res. 2012.
PMID: 23226620
Free PMC article.
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Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance.
Zhang H, Prado K, Zhang KX, Peek EM, Lee J, Wang X, Huang J, Li G, Pellegrini M, Chin AI.
Zhang H, et al. Among authors: peek em.
Clin Cancer Res. 2016 Nov 1;22(21):5349-5361. doi: 10.1158/1078-0432.CCR-15-2581. Epub 2016 May 17.
Clin Cancer Res. 2016.
PMID: 27189164
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