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Amphiphilic 1-deoxynojirimycin derivatives through click strategies for chemical chaperoning in N370S Gaucher cells.
Diot JD, Garcia Moreno I, Twigg G, Ortiz Mellet C, Haupt K, Butters TD, Kovensky J, Gouin SG. Diot JD, et al. Among authors: ortiz mellet c. J Org Chem. 2011 Oct 7;76(19):7757-68. doi: 10.1021/jo201125x. Epub 2011 Aug 29. J Org Chem. 2011. PMID: 21830816
.; Aguilar-Moncayo, M.; Ninomiya, H.; Ohno, K.; Garcia-Moreno, M. I.; Ortiz Mellet, C.; Garcia Fernandez, J. M.; Suzuki, Y. ChemBioChem 2009, 10, 2780), in vitro inhibition of beta-GCase measured for the compounds did not correlate with the cellular chaperone …
.; Aguilar-Moncayo, M.; Ninomiya, H.; Ohno, K.; Garcia-Moreno, M. I.; Ortiz Mellet, C.; Garcia Fernandez, J. M.; Suzuki …
Serine-/Cysteine-Based sp2-Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma.
González-Cuesta M, Lai AC, Chi PY, Hsu IL, Liu NT, Wu KC, García Fernández JM, Chang YJ, Ortiz Mellet C. González-Cuesta M, et al. Among authors: ortiz mellet c. J Med Chem. 2023 Apr 13;66(7):4768-4783. doi: 10.1021/acs.jmedchem.2c01948. Epub 2023 Mar 23. J Med Chem. 2023. PMID: 36958376 Free PMC article.
Scalable syntheses of both enantiomers of DNJNAc and DGJNAc from glucuronolactone: the effect of N-alkylation on hexosaminidase inhibition.
Glawar AF, Best D, Ayers BJ, Miyauchi S, Nakagawa S, Aguilar-Moncayo M, García Fernández JM, Ortiz Mellet C, Crabtree EV, Butters TD, Wilson FX, Kato A, Fleet GW. Glawar AF, et al. Among authors: ortiz mellet c. Chemistry. 2012 Jul 23;18(30):9341-59. doi: 10.1002/chem.201200110. Epub 2012 Jun 26. Chemistry. 2012. PMID: 22736508
148 results