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AAV8-mediated long-term expression of human LCAT significantly improves lipid profiles in hCETP;Ldlr(+/-) mice.
Chen Z, Chu D, Castro-Perez JM, Ni W, Zhang A, Krsmanovic ML, Xie D, Shah V, Stout SJ, McLaren DG, Stefanni AC, Lee SH, Roddy TP, Plump AS, Hubbard BK, Vogt TF, Zhou HH. Chen Z, et al. Among authors: hubbard bk. J Cardiovasc Transl Res. 2011 Dec;4(6):801-10. doi: 10.1007/s12265-011-9309-8. Epub 2011 Aug 6. J Cardiovasc Transl Res. 2011. PMID: 21822774
Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters.
Chen Z, Wang SP, Krsmanovic ML, Castro-Perez J, Gagen K, Mendoza V, Rosa R, Shah V, He T, Stout SJ, Geoghagen NS, Lee SH, McLaren DG, Wang L, Roddy TP, Plump AS, Hubbard BK, Sinz CJ, Johns DG. Chen Z, et al. Among authors: hubbard bk. Metabolism. 2012 Apr;61(4):470-81. doi: 10.1016/j.metabol.2011.08.006. Epub 2011 Oct 14. Metabolism. 2012. PMID: 22001333
Validation of human ApoB and ApoAI immunoturbidity assays for non-human primate dyslipidemia and atherosclerosis research.
Chen Z, Strack AM, Stefanni AC, Chen Y, Wu W, Pan Y, Urosevic-Price O, Wang L, McLaughlin T, Geoghagen N, Lassman ME, Roddy TP, Wong KK, Hubbard BK, Flattery AM. Chen Z, et al. Among authors: hubbard bk. J Cardiovasc Transl Res. 2011 Jun;4(3):373-83. doi: 10.1007/s12265-011-9264-4. Epub 2011 Mar 11. J Cardiovasc Transl Res. 2011. PMID: 21394531
The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species.
McLaren DG, He T, Wang SP, Mendoza V, Rosa R, Gagen K, Bhat G, Herath K, Miller PL, Stribling S, Taggart A, Imbriglio J, Liu J, Chen D, Pinto S, Balkovec JM, DeVita RJ, Marsh DJ, Castro-Perez JM, Strack A, Johns DG, Previs SF, Hubbard BK, Roddy TP. McLaren DG, et al. Among authors: hubbard bk. J Lipid Res. 2011 Jun;52(6):1150-1161. doi: 10.1194/jlr.M011049. Epub 2011 Mar 17. J Lipid Res. 2011. PMID: 21415123 Free PMC article.
Identifying static and kinetic lipid phenotypes by high resolution UPLC-MS: unraveling diet-induced changes in lipid homeostasis by coupling metabolomics and fluxomics.
Castro-Perez JM, Roddy TP, Shah V, McLaren DG, Wang SP, Jensen K, Vreeken RJ, Hankemeier T, Johns DG, Previs SF, Hubbard BK. Castro-Perez JM, et al. Among authors: hubbard bk. J Proteome Res. 2011 Sep 2;10(9):4281-90. doi: 10.1021/pr200480g. Epub 2011 Aug 4. J Proteome Res. 2011. PMID: 21744776
Attenuation of Slc27a5 gene expression followed by LC-MS measurement of bile acid reconjugation using metabolomics and a stable isotope tracer strategy.
Castro-Perez JM, Roddy TP, Shah V, Wang SP, Ouyang X, Ogawa A, McLaren DG, Tadin-Strapps M, Robinson MJ, Bartz SR, Ason B, Chen Y, Previs SF, Wong KK, Vreeken RJ, Johns DG, Hubbard BK, Hankemeier T, Mitnaul L. Castro-Perez JM, et al. Among authors: hubbard bk. J Proteome Res. 2011 Oct 7;10(10):4683-91. doi: 10.1021/pr200475g. Epub 2011 Aug 26. J Proteome Res. 2011. PMID: 21819150
Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia.
Yin W, Carballo-Jane E, McLaren DG, Mendoza VH, Gagen K, Geoghagen NS, McNamara LA, Gorski JN, Eiermann GJ, Petrov A, Wolff M, Tong X, Wilsie LC, Akiyama TE, Chen J, Thankappan A, Xue J, Ping X, Andrews G, Wickham LA, Gai CL, Trinh T, Kulick AA, Donnelly MJ, Voronin GO, Rosa R, Cumiskey AM, Bekkari K, Mitnaul LJ, Puig O, Chen F, Raubertas R, Wong PH, Hansen BC, Koblan KS, Roddy TP, Hubbard BK, Strack AM. Yin W, et al. Among authors: hubbard bk. J Lipid Res. 2012 Jan;53(1):51-65. doi: 10.1194/jlr.M019927. Epub 2011 Oct 23. J Lipid Res. 2012. PMID: 22021650 Free PMC article.
89 results