Luthi-Carter R - Search Results

1

What have we learned from gene expression profiles in Huntington's disease?

Seredenina T, Luthi-Carter R. Seredenina T, et al. Neurobiol Dis. 2012 Jan;45(1):83-98. doi: 10.1016/j.nbd.2011.07.001. Epub 2011 Jul 12. Neurobiol Dis. 2012. PMID: 21820514 Review.

2

Diminished activity-dependent brain-derived neurotrophic factor expression underlies cortical neuron microcircuit hypoconnectivity resulting from exposure to mutant huntingtin fragments.

Gambazzi L, Gokce O, Seredenina T, Katsyuba E, Runne H, Markram H, Giugliano M, Luthi-Carter R. Gambazzi L, et al. J Pharmacol Exp Ther. 2010 Oct;335(1):13-22. doi: 10.1124/jpet.110.167551. Epub 2010 Jul 12. J Pharmacol Exp Ther. 2010. PMID: 20624994

3

Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease.

Tang B, Seredenina T, Coppola G, Kuhn A, Geschwind DH, Luthi-Carter R, Thomas EA. Tang B, et al. Neurobiol Dis. 2011 Jun;42(3):459-67. doi: 10.1016/j.nbd.2011.02.008. Epub 2011 Feb 18. Neurobiol Dis. 2011. PMID: 21334439 Free PMC article.

4

Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation.

Seredenina T, Gokce O, Luthi-Carter R. Seredenina T, et al. PLoS One. 2011;6(7):e22231. doi: 10.1371/journal.pone.0022231. Epub 2011 Jul 14. PLoS One. 2011. PMID: 21779398 Free PMC article.

5

Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression.

Meylan EM, Breuillaud L, Seredenina T, Magistretti PJ, Halfon O, Luthi-Carter R, Cardinaux JR. Meylan EM, et al. Among authors: luthi carter r. Transl Psychiatry. 2016 Jul 12;6(7):e852. doi: 10.1038/tp.2016.116. Transl Psychiatry. 2016. PMID: 27404284 Free PMC article.

6

Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.

Labbadia J, Cunliffe H, Weiss A, Katsyuba E, Sathasivam K, Seredenina T, Woodman B, Moussaoui S, Frentzel S, Luthi-Carter R, Paganetti P, Bates GP. Labbadia J, et al. J Clin Invest. 2011 Aug;121(8):3306-19. doi: 10.1172/JCI57413. Epub 2011 Jul 25. J Clin Invest. 2011. PMID: 21785217 Free PMC article.

7

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.

Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Jiang M, et al. Nat Med. 2011 Dec 18;18(1):153-8. doi: 10.1038/nm.2558. Nat Med. 2011. PMID: 22179319 Free PMC article.

8

HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.

Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, Osborne GF, Wadel K, Touller C, Butler R, Robertson J, Franklin SA, Smith DL, Park L, Marks PA, Wanker EE, Olson EN, Luthi-Carter R, van der Putten H, Beaumont V, Bates GP. Mielcarek M, et al. PLoS Biol. 2013 Nov;11(11):e1001717. doi: 10.1371/journal.pbio.1001717. Epub 2013 Nov 26. PLoS Biol. 2013. PMID: 24302884 Free PMC article.

9

HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.

Mielcarek M, Seredenina T, Stokes MP, Osborne GF, Landles C, Inuabasi L, Franklin SA, Silva JC, Luthi-Carter R, Beaumont V, Bates GP. Mielcarek M, et al. PLoS One. 2013 Nov 22;8(11):e80849. doi: 10.1371/journal.pone.0080849. eCollection 2013. PLoS One. 2013. PMID: 24278330 Free PMC article.

10

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.

Kuhn A, Goldstein DR, Hodges A, Strand AD, Sengstag T, Kooperberg C, Becanovic K, Pouladi MA, Sathasivam K, Cha JH, Hannan AJ, Hayden MR, Leavitt BR, Dunnett SB, Ferrante RJ, Albin R, Shelbourne P, Delorenzi M, Augood SJ, Faull RL, Olson JM, Bates GP, Jones L, Luthi-Carter R. Kuhn A, et al. Hum Mol Genet. 2007 Aug 1;16(15):1845-61. doi: 10.1093/hmg/ddm133. Epub 2007 May 21. Hum Mol Genet. 2007. PMID: 17519223

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