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Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.
J Am Chem Soc. 2011 Aug 31;133(34):13311-3. doi: 10.1021/ja205655w. Epub 2011 Aug 9.
J Am Chem Soc. 2011.
PMID: 21815669
Free PMC article.
Coupled Biosynthesis of Volatiles and Salinosporamide A in Salinispora tropica.
Groenhagen U, Leandrini De Oliveira AL, Fielding E, Moore BS, Schulz S.
Groenhagen U, et al.
Chembiochem. 2016 Oct 17;17(20):1978-1985. doi: 10.1002/cbic.201600388. Epub 2016 Sep 6.
Chembiochem. 2016.
PMID: 27490971
Free PMC article.
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Prephenate decarboxylases: a new prephenate-utilizing enzyme family that performs nonaromatizing decarboxylation en route to diverse secondary metabolites.
Mahlstedt S, Fielding EN, Moore BS, Walsh CT.
Mahlstedt S, et al. Among authors: fielding en.
Biochemistry. 2010 Oct 26;49(42):9021-3. doi: 10.1021/bi101457h.
Biochemistry. 2010.
PMID: 20863139
Free PMC article.
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Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.
Chen PY, Adak S, Chekan JR, Liscombe DK, Miyanaga A, Bernhardt P, Diethelm S, Fielding EN, George JH, Miles ZD, Murray LAM, Steele TS, Winter JM, Noel JP, Moore BS.
Chen PY, et al. Among authors: fielding en.
Biochemistry. 2022 Sep 6;61(17):1844-1852. doi: 10.1021/acs.biochem.2c00338. Epub 2022 Aug 19.
Biochemistry. 2022.
PMID: 35985031
Free PMC article.
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Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC.
Fielding EN, Widboom PF, Bruner SD.
Fielding EN, et al.
Biochemistry. 2007 Dec 11;46(49):13994-4000. doi: 10.1021/bi701148b. Epub 2007 Nov 16.
Biochemistry. 2007.
PMID: 18004875
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Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis.
Widboom PF, Fielding EN, Liu Y, Bruner SD.
Widboom PF, et al. Among authors: fielding en.
Nature. 2007 May 17;447(7142):342-5. doi: 10.1038/nature05702.
Nature. 2007.
PMID: 17507985
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Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Li K, Fielding EN, Condurso HL, Bruner SD.
Li K, et al. Among authors: fielding en.
Acta Crystallogr D Struct Biol. 2017 Jul 1;73(Pt 7):573-580. doi: 10.1107/S2059798317007045. Epub 2017 Jun 30.
Acta Crystallogr D Struct Biol. 2017.
PMID: 28695857
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