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Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.
Miyanaga A, Janso JE, McDonald L, He M, Liu H, Barbieri L, Eustáquio AS, Fielding EN, Carter GT, Jensen PR, Feng X, Leighton M, Koehn FE, Moore BS. Miyanaga A, et al. Among authors: barbieri l. J Am Chem Soc. 2011 Aug 31;133(34):13311-3. doi: 10.1021/ja205655w. Epub 2011 Aug 9. J Am Chem Soc. 2011. PMID: 21815669 Free PMC article.
Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines.
Toral-Barza L, Zhang WG, Huang X, McDonald LA, Salaski EJ, Barbieri LR, Ding WD, Krishnamurthy G, Hu YB, Lucas J, Bernan VS, Cai P, Levin JI, Mansour TS, Gibbons JJ, Abraham RT, Yu K. Toral-Barza L, et al. Among authors: barbieri lr. Mol Cancer Ther. 2007 Nov;6(11):3028-38. doi: 10.1158/1535-7163.MCT-07-0211. Epub 2007 Nov 7. Mol Cancer Ther. 2007. PMID: 17989320
Fermentative production of self-toxic fungal secondary metabolites.
Singh MP, Leighton MM, Barbieri LR, Roll DM, Urbance SE, Hoshan L, McDonald LA. Singh MP, et al. Among authors: barbieri lr. J Ind Microbiol Biotechnol. 2010 Apr;37(4):335-40. doi: 10.1007/s10295-009-0678-9. Epub 2009 Dec 24. J Ind Microbiol Biotechnol. 2010. PMID: 20033470
Identification and analysis of bacterial protein secretion inhibitors utilizing a SecA-LacZ reporter fusion system.
Alksne LE, Burgio P, Hu W, Feld B, Singh MP, Tuckman M, Petersen PJ, Labthavikul P, McGlynn M, Barbieri L, McDonald L, Bradford P, Dushin RG, Rothstein D, Projan SJ. Alksne LE, et al. Among authors: barbieri l. Antimicrob Agents Chemother. 2000 Jun;44(6):1418-27. doi: 10.1128/AAC.44.6.1418-1427.2000. Antimicrob Agents Chemother. 2000. PMID: 10817687 Free PMC article.
581 results