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129 results

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Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M. Jiang Y, et al. Among authors: cabot mc. Cancer Biol Ther. 2011 Oct 1;12(7):574-85. doi: 10.4161/cbt.12.7.15971. Epub 2011 Oct 1. Cancer Biol Ther. 2011. PMID: 21795855 Free PMC article.
Ceramide-based therapeutics for the treatment of cancer.
Barth BM, Cabot MC, Kester M. Barth BM, et al. Among authors: cabot mc. Anticancer Agents Med Chem. 2011 Nov;11(9):911-9. doi: 10.2174/187152011797655177. Anticancer Agents Med Chem. 2011. PMID: 21707481 Review.
Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance.
Barth BM, Gustafson SJ, Young MM, Fox TE, Shanmugavelandy SS, Kaiser JM, Cabot MC, Kester M, Kuhn TB. Barth BM, et al. Among authors: cabot mc. Cancer Biol Ther. 2010 Dec 1;10(11):1126-36. doi: 10.4161/cbt.10.11.13438. Epub 2010 Dec 1. Cancer Biol Ther. 2010. PMID: 20935456 Free PMC article.
Gaucher's disease and cancer: a sphingolipid perspective.
Barth BM, Shanmugavelandy SS, Tacelosky DM, Kester M, Morad SA, Cabot MC. Barth BM, et al. Among authors: cabot mc. Crit Rev Oncog. 2013;18(3):221-34. doi: 10.1615/critrevoncog.2013005814. Crit Rev Oncog. 2013. PMID: 23510065 Free PMC article. Review.
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Morad SA, Tan SF, Feith DJ, Kester M, Claxton DF, Loughran TP Jr, Barth BM, Fox TE, Cabot MC. Morad SA, et al. Among authors: cabot mc. Biochim Biophys Acta. 2015 Jul;1851(7):919-28. doi: 10.1016/j.bbalip.2015.03.001. Epub 2015 Mar 10. Biochim Biophys Acta. 2015. PMID: 25769964 Free PMC article.
Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia.
Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC. Morad SA, et al. Among authors: cabot mc. J Lipid Res. 2016 Jul;57(7):1231-42. doi: 10.1194/jlr.M067389. Epub 2016 May 2. J Lipid Res. 2016. PMID: 27140664 Free PMC article.
Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, Liao J, Yun J, Kester M, Claxton DF, Wang HG, Cabot MC, Schuchman EH, Levine RL, Feith DJ, Loughran TP Jr. Tan SF, et al. Among authors: cabot mc. Oncotarget. 2016 Dec 13;7(50):83208-83222. doi: 10.18632/oncotarget.13079. Oncotarget. 2016. PMID: 27825124 Free PMC article.
Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation.
Barth BM, Keasey NR, Wang X, Shanmugavelandy SS, Rampal R, Hricik T, Cabot MC, Kester M, Wang HG, Shultz LD, Tallman MS, Levine RL, Loughran TP Jr, Claxton DF. Barth BM, et al. Among authors: cabot mc. J Leuk (Los Angel). 2014 Sep;2(3):146. doi: 10.4172/2329-6917.1000146. Epub 2014 Jul 25. J Leuk (Los Angel). 2014. PMID: 28239612 Free PMC article.
129 results