Smid K - Search Results

1

DNA copy number profiles correlate with outcome in colorectal cancer patients treated with fluoropyrimidine/antifolate-based regimens.

Leon LG, Giovannetti E, Smid K, van Houte BP, Hanauske AR, Giaccone G, Peters GJ. Leon LG, et al. Among authors: smid k. Curr Drug Metab. 2011 Dec;12(10):956-65. doi: 10.2174/138920011798062337. Curr Drug Metab. 2011. PMID: 21787269 Review.

2

Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression after administration of 5-fluorouracil to patients with colorectal cancer.

Mauritz R, van Groeningen CJ, Smid K, Jansen G, Pinedo HM, Peters GJ. Mauritz R, et al. Among authors: smid k. Int J Cancer. 2007 Jun 15;120(12):2609-12. doi: 10.1002/ijc.22626. Int J Cancer. 2007. PMID: 17330233 Free article.

3

Polymorphisms in the enhancer region of the thymidylate synthase gene are associated with thymidylate synthase levels in normal tissues but not in malignant tissues of patients with colorectal cancer.

Mauritz R, Giovannetti E, Beumer IJ, Smid K, Van Groeningen CJ, Pinedo HM, Peters GJ. Mauritz R, et al. Among authors: smid k. Clin Colorectal Cancer. 2009 Jul;8(3):146-54. doi: 10.3816/CCC.2009.n.024. Clin Colorectal Cancer. 2009. PMID: 19632929

4

Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors.

Van der Wilt CL, Pinedo HM, Smid K, Peters GJ. Van der Wilt CL, et al. Among authors: smid k. Cancer Res. 1992 Sep 15;52(18):4922-8. Cancer Res. 1992. PMID: 1516048

5

Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.

Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S, Pinedo HM. Peters GJ, et al. Among authors: smid k. J Clin Oncol. 1994 Oct;12(10):2035-42. doi: 10.1200/JCO.1994.12.10.2035. J Clin Oncol. 1994. PMID: 7931471 Clinical Trial.

6

5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers.

Noordhuis P, Holwerda U, Van der Wilt CL, Van Groeningen CJ, Smid K, Meijer S, Pinedo HM, Peters GJ. Noordhuis P, et al. Among authors: smid k. Ann Oncol. 2004 Jul;15(7):1025-32. doi: 10.1093/annonc/mdh264. Ann Oncol. 2004. PMID: 15205195 Free article. Clinical Trial.

7

Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase.

Smorenburg CH, Peters GJ, van Groeningen CJ, Noordhuis P, Smid K, van Riel AM, Dercksen W, Pinedo HM, Giaccone G. Smorenburg CH, et al. Among authors: smid k. Ann Oncol. 2006 Jan;17(1):35-42. doi: 10.1093/annonc/mdj046. Epub 2005 Oct 26. Ann Oncol. 2006. PMID: 16251201 Free article. Clinical Trial.

8

Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells.

Tekle C, Giovannetti E, Sigmond J, Graff JR, Smid K, Peters GJ. Tekle C, et al. Among authors: smid k. Br J Cancer. 2008 Sep 2;99(5):750-9. doi: 10.1038/sj.bjc.6604566. Epub 2008 Aug 19. Br J Cancer. 2008. PMID: 18728666 Free PMC article.

9

Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin.

Giovannetti E, Zucali PA, Assaraf YG, Leon LG, Smid K, Alecci C, Giancola F, Destro A, Gianoncelli L, Lorenzi E, Roncalli M, Santoro A, Peters GJ. Giovannetti E, et al. Among authors: smid k. Br J Cancer. 2011 Nov 8;105(10):1542-53. doi: 10.1038/bjc.2011.400. Epub 2011 Oct 4. Br J Cancer. 2011. PMID: 21970874 Free PMC article.

10

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia.

Maftouh M, Avan A, Sciarrillo R, Granchi C, Leon LG, Rani R, Funel N, Smid K, Honeywell R, Boggi U, Minutolo F, Peters GJ, Giovannetti E. Maftouh M, et al. Among authors: smid k. Br J Cancer. 2014 Jan 7;110(1):172-82. doi: 10.1038/bjc.2013.681. Epub 2013 Oct 31. Br J Cancer. 2014. PMID: 24178759 Free PMC article.

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