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New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.
Anzini M, Valenti S, Braile C, Cappelli A, Vomero S, Alcaro S, Ortuso F, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Daniele S, Martini C, Ghelardini C, Di Cesare Mannelli L, Giorgi G, Mascia MP, Biggio G. Anzini M, et al. Among authors: limongelli v. J Med Chem. 2011 Aug 25;54(16):5694-711. doi: 10.1021/jm2001597. Epub 2011 Jul 27. J Med Chem. 2011. PMID: 21751815
Ethyl 8-fluoro-6-(3-nitrophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate as novel, highly potent, and safe antianxiety agent.
Anzini M, Braile C, Valenti S, Cappelli A, Vomero S, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Ghelardini C, Norcini M, Makovec F, Giorgi G, Ian Fryer R. Anzini M, et al. Among authors: limongelli v. J Med Chem. 2008 Aug 14;51(15):4730-43. doi: 10.1021/jm8002944. Epub 2008 Jul 19. J Med Chem. 2008. PMID: 18637672
Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.
Simoni D, Gebbia N, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Provera S, Marchioro C, Tolomeo M, Marinelli L, Limongelli V, Novellino E, Kwaasi A, Dunford J, Buccheri S, Caccamo N, Dieli F. Simoni D, et al. Among authors: limongelli v. J Med Chem. 2008 Nov 13;51(21):6800-7. doi: 10.1021/jm801003y. Epub 2008 Oct 21. J Med Chem. 2008. PMID: 18937434
Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models.
Nuti E, Casalini F, Avramova SI, Santamaria S, Fabbi M, Ferrini S, Marinelli L, La Pietra V, Limongelli V, Novellino E, Cercignani G, Orlandini E, Nencetti S, Rossello A. Nuti E, et al. Among authors: limongelli v. J Med Chem. 2010 Mar 25;53(6):2622-35. doi: 10.1021/jm901868z. J Med Chem. 2010. PMID: 20180536
77 results