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Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.
Ill-Raga G, Palomer E, Wozniak MA, Ramos-Fernández E, Bosch-Morató M, Tajes M, Guix FX, Galán JJ, Clarimón J, Antúnez C, Real LM, Boada M, Itzhaki RF, Fandos C, Muñoz FJ. Ill-Raga G, et al. Among authors: guix fx. PLoS One. 2011;6(6):e21456. doi: 10.1371/journal.pone.0021456. Epub 2011 Jun 28. PLoS One. 2011. PMID: 21738672 Free PMC article.
Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells.
Ill-Raga G, Ramos-Fernández E, Guix FX, Tajes M, Bosch-Morató M, Palomer E, Godoy J, Belmar S, Cerpa W, Simpkins JW, Inestrosa And NC, Muñoz FJ. Ill-Raga G, et al. Among authors: guix fx. J Alzheimers Dis. 2010;22(2):641-52. doi: 10.3233/JAD-2010-100474. J Alzheimers Dis. 2010. PMID: 20858976
Nitro-oxidative stress after neuronal ischemia induces protein nitrotyrosination and cell death.
Tajes M, Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Galán AM, Alameda F, Escolar G, Opazo C, Planas A, Roquer J, Valverde MA, Muñoz FJ. Tajes M, et al. Among authors: guix fx. Oxid Med Cell Longev. 2013;2013:826143. doi: 10.1155/2013/826143. Epub 2013 Aug 1. Oxid Med Cell Longev. 2013. PMID: 23983901 Free PMC article.
Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease.
Tajes M, Eraso-Pichot A, Rubio-Moscardó F, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Guix FX, Clarimón J, Miscione GP, Boada M, Gil-Gómez G, Suzuki T, Molina H, Villà-Freixa J, Vicente R, Muñoz FJ. Tajes M, et al. Among authors: guix fx. J Alzheimers Dis. 2014;41(1):273-88. doi: 10.3233/JAD-131685. J Alzheimers Dis. 2014. PMID: 24614897
30 results