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Identification of small-molecule inhibitors of Trypansoma cruzi replication.
Germain AR, Carmody LC, Dockendorff C, Galan-Rodriguez C, Rodriguez A, Johnston S, Bittker JA, MacPherson L, Dandapani S, Palmer M, Schreiber SL, Munoz B. Germain AR, et al. Among authors: galan rodriguez c. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7197-200. doi: 10.1016/j.bmcl.2011.09.057. Epub 2011 Sep 29. Bioorg Med Chem Lett. 2011. PMID: 22018462
The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing.
Diaz-Gonzalez R, Kuhlmann FM, Galan-Rodriguez C, Madeira da Silva L, Saldivia M, Karver CE, Rodriguez A, Beverley SM, Navarro M, Pollastri MP. Diaz-Gonzalez R, et al. Among authors: galan rodriguez c. PLoS Negl Trop Dis. 2011 Aug;5(8):e1297. doi: 10.1371/journal.pntd.0001297. Epub 2011 Aug 23. PLoS Negl Trop Dis. 2011. PMID: 21886855 Free PMC article.
Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 3.
Carmody LC, Germain A, Barker D, Galan-Rodriguez C, Bettiol E, Rodriguez A, MacPherson L, Palmer M, Schreiber SL. Carmody LC, et al. Among authors: galan rodriguez c. 2010 Mar 25 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Mar 25 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21735611 Free Books & Documents. Review.
Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 1.
Carmody LC, Germain A, Barker D, Galan-Rodriguez C, Bettiol E, Rodriguez A, MacPherson L, Palmer M, Schreiber SL. Carmody LC, et al. Among authors: galan rodriguez c. 2010 Mar 26 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Mar 26 [updated 2011 Mar 11]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21735600 Free Books & Documents. Review.
Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection.
Carmody LC, Germain A, Barker D, Galan-Rodriguez C, Bettiol E, Rodriguez A, MacPherson L, Palmer M, Schreiber SL. Carmody LC, et al. Among authors: galan rodriguez c. 2010 Mar 25 [updated 2011 Feb 10]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2010 Mar 25 [updated 2011 Feb 10]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 21634083 Free Books & Documents. Review.