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Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease.
Besler C, Heinrich K, Rohrer L, Doerries C, Riwanto M, Shih DM, Chroni A, Yonekawa K, Stein S, Schaefer N, Mueller M, Akhmedov A, Daniil G, Manes C, Templin C, Wyss C, Maier W, Tanner FC, Matter CM, Corti R, Furlong C, Lusis AJ, von Eckardstein A, Fogelman AM, Lüscher TF, Landmesser U. Besler C, et al. Among authors: chroni a. J Clin Invest. 2011 Jul;121(7):2693-708. doi: 10.1172/JCI42946. Epub 2011 Jun 23. J Clin Invest. 2011. PMID: 21701070 Free PMC article.
Carboxyl terminus of apolipoprotein A-I (ApoA-I) is necessary for the transport of lipid-free ApoA-I but not prelipidated ApoA-I particles through aortic endothelial cells.
Ohnsorg PM, Rohrer L, Perisa D, Kateifides A, Chroni A, Kardassis D, Zannis VI, von Eckardstein A. Ohnsorg PM, et al. Among authors: chroni a. J Biol Chem. 2011 Mar 11;286(10):7744-7754. doi: 10.1074/jbc.M110.193524. Epub 2011 Jan 5. J Biol Chem. 2011. PMID: 21209084 Free PMC article.
The central helices of ApoA-I can promote ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-type ApoA-I are required for lipid efflux in vitro and high density lipoprotein formation in vivo.
Chroni A, Liu T, Gorshkova I, Kan HY, Uehara Y, Von Eckardstein A, Zannis VI. Chroni A, et al. J Biol Chem. 2003 Feb 28;278(9):6719-30. doi: 10.1074/jbc.M205232200. Epub 2002 Dec 17. J Biol Chem. 2003. PMID: 12488454 Free article.
Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations.
Holleboom AG, Daniil G, Fu X, Zhang R, Hovingh GK, Schimmel AW, Kastelein JJ, Stroes ES, Witztum JL, Hutten BA, Tsimikas S, Hazen SL, Chroni A, Kuivenhoven JA. Holleboom AG, et al. Among authors: chroni a. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):3066-75. doi: 10.1161/ATVBAHA.112.255711. Epub 2012 Sep 27. Arterioscler Thromb Vasc Biol. 2012. PMID: 23023370 Free PMC article.
Identification and characterization of a rare variant in apolipoprotein A-IV, p.(V336M), and evaluation of HDL functionality in a Greek cohort with extreme HDL cholesterol levels.
Chroni A, Rallidis L, Vassou D, Gkolfinopoulou C, Papakosta P, Zervou MI, Goulielmos GN, Kiouri E, Pappa D, Eliopoulos E, Kardassis D. Chroni A, et al. Arch Biochem Biophys. 2020 Dec 15;696:108655. doi: 10.1016/j.abb.2020.108655. Epub 2020 Oct 29. Arch Biochem Biophys. 2020. PMID: 33130088
HDL biogenesis, remodeling, and catabolism.
Zannis VI, Fotakis P, Koukos G, Kardassis D, Ehnholm C, Jauhiainen M, Chroni A. Zannis VI, et al. Among authors: chroni a. Handb Exp Pharmacol. 2015;224:53-111. doi: 10.1007/978-3-319-09665-0_2. Handb Exp Pharmacol. 2015. PMID: 25522986 Review.
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