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Drug targets from genetics: α-synuclein.
Danzer KM, McLean PJ. Danzer KM, et al. Among authors: mclean pj. CNS Neurol Disord Drug Targets. 2011 Sep 1;10(6):712-23. doi: 10.2174/187152711797247867. CNS Neurol Disord Drug Targets. 2011. PMID: 21838671 Free PMC article. Review.
Dopamine-induced conformational changes in alpha-synuclein.
Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira LM, Quintas A, McLean PJ, Hyman BT. Outeiro TF, et al. Among authors: mclean pj. PLoS One. 2009 Sep 4;4(9):e6906. doi: 10.1371/journal.pone.0006906. PLoS One. 2009. PMID: 19730729 Free PMC article.
Exosomal cell-to-cell transmission of alpha synuclein oligomers.
Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Danzer KM, et al. Among authors: mclean pj. Mol Neurodegener. 2012 Aug 24;7:42. doi: 10.1186/1750-1326-7-42. Mol Neurodegener. 2012. PMID: 22920859 Free PMC article.
Direct detection of alpha synuclein oligomers in vivo.
Dimant H, Kalia SK, Kalia LV, Zhu LN, Kibuuka L, Ebrahimi-Fakhari D, McFarland NR, Fan Z, Hyman BT, McLean PJ. Dimant H, et al. Among authors: mclean pj. Acta Neuropathol Commun. 2013 May 9;1:6. doi: 10.1186/2051-5960-1-6. Acta Neuropathol Commun. 2013. PMID: 24252244 Free PMC article.
In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species.
Kiechle M, von Einem B, Höfs L, Voehringer P, Grozdanov V, Markx D, Parlato R, Wiesner D, Mayer B, Sakk O, Baumann B, Lukassen S, Liss B, Ekici AB, Ludolph AC, Walther P, Ferger B, McLean PJ, Falkenburger BH, Weishaupt JH, Danzer KM. Kiechle M, et al. Among authors: mclean pj. Cell Rep. 2019 Nov 26;29(9):2862-2874.e9. doi: 10.1016/j.celrep.2019.10.089. Cell Rep. 2019. PMID: 31775051 Free article.
114 results