Wiederhold KH - Search Results

1

The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.

Wiessner C, Wiederhold KH, Tissot AC, Frey P, Danner S, Jacobson LH, Jennings GT, Lüönd R, Ortmann R, Reichwald J, Zurini M, Mir A, Bachmann MF, Staufenbiel M. Wiessner C, et al. Among authors: wiederhold kh. J Neurosci. 2011 Jun 22;31(25):9323-31. doi: 10.1523/JNEUROSCI.0293-11.2011. J Neurosci. 2011. PMID: 21697382 Free PMC article.

2

Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice.

Bondolfi L, Calhoun M, Ermini F, Kuhn HG, Wiederhold KH, Walker L, Staufenbiel M, Jucker M. Bondolfi L, et al. Among authors: wiederhold kh. J Neurosci. 2002 Jan 15;22(2):515-22. doi: 10.1523/JNEUROSCI.22-02-00515.2002. J Neurosci. 2002. PMID: 11784797 Free PMC article.

3

Age-dependent cerebrovascular abnormalities and blood flow disturbances in APP23 mice modeling Alzheimer's disease.

Beckmann N, Schuler A, Mueggler T, Meyer EP, Wiederhold KH, Staufenbiel M, Krucker T. Beckmann N, et al. Among authors: wiederhold kh. J Neurosci. 2003 Sep 17;23(24):8453-9. doi: 10.1523/JNEUROSCI.23-24-08453.2003. J Neurosci. 2003. PMID: 13679413 Free PMC article.

4

Expression of complement system components during aging and amyloid deposition in APP transgenic mice.

Reichwald J, Danner S, Wiederhold KH, Staufenbiel M. Reichwald J, et al. Among authors: wiederhold kh. J Neuroinflammation. 2009 Nov 17;6:35. doi: 10.1186/1742-2094-6-35. J Neuroinflammation. 2009. PMID: 19917141 Free PMC article.

5

Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.

Abramowski D, Rabe S, Upadhaya AR, Reichwald J, Danner S, Staab D, Capetillo-Zarate E, Yamaguchi H, Saido TC, Wiederhold KH, Thal DR, Staufenbiel M. Abramowski D, et al. Among authors: wiederhold kh. J Neurosci. 2012 Jan 25;32(4):1273-83. doi: 10.1523/JNEUROSCI.4586-11.2012. J Neurosci. 2012. PMID: 22279212 Free PMC article.

6

Expression of human beta-secretase in the mouse brain increases the steady-state level of beta-amyloid.

Bodendorf U, Danner S, Fischer F, Stefani M, Sturchler-Pierrat C, Wiederhold KH, Staufenbiel M, Paganetti P. Bodendorf U, et al. Among authors: wiederhold kh. J Neurochem. 2002 Mar;80(5):799-806. doi: 10.1046/j.0022-3042.2002.00770.x. J Neurochem. 2002. PMID: 11948243 Free article.

7

Molecular imaging of amyloid beta peptides in mouse brain sections using mass spectrometry.

Stoeckli M, Staab D, Staufenbiel M, Wiederhold KH, Signor L. Stoeckli M, et al. Among authors: wiederhold kh. Anal Biochem. 2002 Dec 1;311(1):33-9. doi: 10.1016/s0003-2697(02)00386-x. Anal Biochem. 2002. PMID: 12441150

8

Neocortical synaptic bouton number is maintained despite robust amyloid deposition in APP23 transgenic mice.

Boncristiano S, Calhoun ME, Howard V, Bondolfi L, Kaeser SA, Wiederhold KH, Staufenbiel M, Jucker M. Boncristiano S, et al. Among authors: wiederhold kh. Neurobiol Aging. 2005 May;26(5):607-13. doi: 10.1016/j.neurobiolaging.2004.06.010. Neurobiol Aging. 2005. PMID: 15708435

9

In vivo detection of amyloid-beta deposits by near-infrared imaging using an oxazine-derivative probe.

Hintersteiner M, Enz A, Frey P, Jaton AL, Kinzy W, Kneuer R, Neumann U, Rudin M, Staufenbiel M, Stoeckli M, Wiederhold KH, Gremlich HU. Hintersteiner M, et al. Among authors: wiederhold kh. Nat Biotechnol. 2005 May;23(5):577-83. doi: 10.1038/nbt1085. Epub 2005 Apr 17. Nat Biotechnol. 2005. PMID: 15834405

10

Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.

Abramowski D, Wiederhold KH, Furrer U, Jaton AL, Neuenschwander A, Runser MJ, Danner S, Reichwald J, Ammaturo D, Staab D, Stoeckli M, Rueeger H, Neumann U, Staufenbiel M. Abramowski D, et al. Among authors: wiederhold kh. J Pharmacol Exp Ther. 2008 Nov;327(2):411-24. doi: 10.1124/jpet.108.140327. Epub 2008 Aug 7. J Pharmacol Exp Ther. 2008. PMID: 18687920

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