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The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.
Wiessner C, Wiederhold KH, Tissot AC, Frey P, Danner S, Jacobson LH, Jennings GT, Lüönd R, Ortmann R, Reichwald J, Zurini M, Mir A, Bachmann MF, Staufenbiel M. Wiessner C, et al. Among authors: staufenbiel m. J Neurosci. 2011 Jun 22;31(25):9323-31. doi: 10.1523/JNEUROSCI.0293-11.2011. J Neurosci. 2011. PMID: 21697382 Free PMC article.
Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis.
Boncristiano S, Calhoun ME, Kelly PH, Pfeifer M, Bondolfi L, Stalder M, Phinney AL, Abramowski D, Sturchler-Pierrat C, Enz A, Sommer B, Staufenbiel M, Jucker M. Boncristiano S, et al. Among authors: staufenbiel m. J Neurosci. 2002 Apr 15;22(8):3234-43. doi: 10.1523/JNEUROSCI.22-08-03234.2002. J Neurosci. 2002. PMID: 11943824 Free PMC article.
Extracellular amyloid formation and associated pathology in neural grafts.
Meyer-Luehmann M, Stalder M, Herzig MC, Kaeser SA, Kohler E, Pfeifer M, Boncristiano S, Mathews PM, Mercken M, Abramowski D, Staufenbiel M, Jucker M. Meyer-Luehmann M, et al. Among authors: staufenbiel m. Nat Neurosci. 2003 Apr;6(4):370-7. doi: 10.1038/nn1022. Nat Neurosci. 2003. PMID: 12598899
214 results