Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

22 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.
Zindell R, Walker ER, Scott J, Amouzegh P, Wu L, Ermann M, Thomson D, Fisher MB, Fullenwider CL, Grbic H, Kaplita P, Linehan B, Patel M, Patel M, Löbbe S, Block S, Albrecht C, Gemkow MJ, Shih DT, Riether D. Zindell R, et al. Among authors: riether d. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4276-80. doi: 10.1016/j.bmcl.2011.05.068. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21689933
Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity.
Ermann M, Riether D, Walker ER, Mushi IF, Jenkins JE, Noya-Marino B, Brewer ML, Taylor MG, Amouzegh P, East SP, Dymock BW, Gemkow MJ, Kahrs AF, Ebneth A, Löbbe S, O'Shea K, Shih DT, Thomson D. Ermann M, et al. Among authors: riether d. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1725-9. doi: 10.1016/j.bmcl.2008.01.042. Epub 2008 Jan 18. Bioorg Med Chem Lett. 2008. PMID: 18255291
Morpholine containing CB2 selective agonists.
Zindell R, Riether D, Bosanac T, Berry A, Gemkow MJ, Ebneth A, Löbbe S, Raymond EL, Thome D, Shih DT, Thomson D. Zindell R, et al. Among authors: riether d. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1604-9. doi: 10.1016/j.bmcl.2009.02.033. Epub 2009 Feb 12. Bioorg Med Chem Lett. 2009. PMID: 19243942
5-Aminomethylbenzimidazoles as potent ITK antagonists.
Riether D, Zindell R, Kowalski JA, Cook BN, Bentzien J, Lombaert SD, Thomson D, Kugler SZ Jr, Skow D, Martin LS, Raymond EL, Khine HH, O'Shea K, Woska JR Jr, Jeanfavre D, Sellati R, Ralph KL, Ahlberg J, Labissiere G, Kashem MA, Pullen SS, Takahashi H. Riether D, et al. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1588-91. doi: 10.1016/j.bmcl.2009.02.012. Epub 2009 Feb 8. Bioorg Med Chem Lett. 2009. PMID: 19246196
1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.
Riether D, Wu L, Cirillo PF, Berry A, Walker ER, Ermann M, Noya-Marino B, Jenkins JE, Albaugh D, Albrecht C, Fisher M, Gemkow MJ, Grbic H, Löbbe S, Möller C, O'Shea K, Sauer A, Shih DT, Thomson DS. Riether D, et al. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2011-6. doi: 10.1016/j.bmcl.2011.02.017. Epub 2011 Feb 25. Bioorg Med Chem Lett. 2011. PMID: 21354795
Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.
Harcken C, Riether D, Kuzmich D, Liu P, Betageri R, Ralph M, Emmanuel M, Reeves JT, Berry A, Souza D, Nelson RM, Kukulka A, Fadra TN, Zuvela-Jelaska L, Dinallo R, Bentzien J, Nabozny GH, Thomson DS. Harcken C, et al. Among authors: riether d. J Med Chem. 2014 Feb 27;57(4):1583-98. doi: 10.1021/jm4019178. Epub 2014 Feb 7. J Med Chem. 2014. PMID: 24506830
Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore.
Razavi H, Riether D, Harcken C, Bentzien J, Dinallo RM, Souza D, Nelson RM, Kukulka A, Fadra-Khan TN, Pack EJ Jr, Zuvela-Jelaska L, Pelletier J, Panzenbeck M, Torcellini CA, Proudfoot JR, Nabozny GH, Thomson DS. Razavi H, et al. Among authors: riether d. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1934-40. doi: 10.1016/j.bmcl.2014.03.005. Epub 2014 Mar 12. Bioorg Med Chem Lett. 2014. PMID: 24656565
Optimization of drug-like properties of nonsteroidal glucocorticoid mimetics and identification of a clinical candidate.
Harcken C, Riether D, Liu P, Razavi H, Patel U, Lee T, Bosanac T, Ward Y, Ralph M, Chen Z, Souza D, Nelson RM, Kukulka A, Fadra-Khan TN, Zuvela-Jelaska L, Patel M, Thomson DS, Nabozny GH. Harcken C, et al. Among authors: riether d. ACS Med Chem Lett. 2014 Nov 20;5(12):1318-23. doi: 10.1021/ml500387y. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516791 Free PMC article.
22 results