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Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.
Bioorg Med Chem Lett. 2011 Jul 15;21(14):4276-80. doi: 10.1016/j.bmcl.2011.05.068. Epub 2011 May 27.
Bioorg Med Chem Lett. 2011.
PMID: 21689933
Time-dependent inhibition and estimation of CYP3A clinical pharmacokinetic drug-drug interactions using plated human cell systems.
Albaugh DR, Fullenwider CL, Fisher MB, Hutzler JM.
Albaugh DR, et al. Among authors: fullenwider cl.
Drug Metab Dispos. 2012 Jul;40(7):1336-44. doi: 10.1124/dmd.112.044644. Epub 2012 Apr 9.
Drug Metab Dispos. 2012.
PMID: 22490230
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Predictive In Vitro-In Vivo Extrapolation for Time Dependent Inhibition of CYP1A2, CYP2C8, CYP2C9, CYP2C19, and CYP2D6 Using Pooled Human Hepatocytes, Human Liver Microsomes, and a Simple Mechanistic Static Model.
Ramsden D, Perloff ES, Whitcher-Johnstone A, Ho T, Patel R, Kozminski KD, Fullenwider CL, Zhang JG.
Ramsden D, et al. Among authors: fullenwider cl.
Drug Metab Dispos. 2022 Feb;50(2):114-127. doi: 10.1124/dmd.121.000718. Epub 2021 Nov 17.
Drug Metab Dispos. 2022.
PMID: 34789487
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Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.
Hutzler JM, Yang YS, Albaugh D, Fullenwider CL, Schmenk J, Fisher MB.
Hutzler JM, et al. Among authors: fullenwider cl.
Drug Metab Dispos. 2012 Feb;40(2):267-75. doi: 10.1124/dmd.111.042861. Epub 2011 Oct 26.
Drug Metab Dispos. 2012.
PMID: 22031625
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Characterization of Correction Factors to Enable Assessment of Clinical Risk from In Vitro CYP3A4 Induction Data and Basic Drug-Drug Interaction Models.
Ramsden D, Fullenwider CL.
Ramsden D, et al. Among authors: fullenwider cl.
Eur J Drug Metab Pharmacokinet. 2022 Jul;47(4):467-482. doi: 10.1007/s13318-022-00763-y. Epub 2022 Mar 28.
Eur J Drug Metab Pharmacokinet. 2022.
PMID: 35344159
Free PMC article.
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Biopharmaceutics permeability classification of lorcaserin, a selective 5-hydroxytryptamine 2C agonist: method suitability and permeability class membership.
Chen C, Ma MG, Fullenwider CL, Chen WG, Sadeque AJ.
Chen C, et al. Among authors: fullenwider cl.
Mol Pharm. 2013 Dec 2;10(12):4739-45. doi: 10.1021/mp400468c. Epub 2013 Oct 29.
Mol Pharm. 2013.
PMID: 24102111
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