Fisher MB - Search Results

1

Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.

Zindell R, Walker ER, Scott J, Amouzegh P, Wu L, Ermann M, Thomson D, Fisher MB, Fullenwider CL, Grbic H, Kaplita P, Linehan B, Patel M, Patel M, Löbbe S, Block S, Albrecht C, Gemkow MJ, Shih DT, Riether D. Zindell R, et al. Among authors: fisher mb. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4276-80. doi: 10.1016/j.bmcl.2011.05.068. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21689933

2

1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.

Riether D, Wu L, Cirillo PF, Berry A, Walker ER, Ermann M, Noya-Marino B, Jenkins JE, Albaugh D, Albrecht C, Fisher M, Gemkow MJ, Grbic H, Löbbe S, Möller C, O'Shea K, Sauer A, Shih DT, Thomson DS. Riether D, et al. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2011-6. doi: 10.1016/j.bmcl.2011.02.017. Epub 2011 Feb 25. Bioorg Med Chem Lett. 2011. PMID: 21354795

3

Piperazinyl-oxadiazoles as selective sphingosine-1-phosphate receptor agonists.

Horan JC, Sanyal S, Choi Y, Hill-Drzewi M, Patnaude L, Anderson S, Fogal S, Mao C, Cook BN, Gueneva-Boucheva K, Fisher MB, Hickey E, Pack E, Bannen LC, Chan DS, Mac MB, Ng SM, Wang Y, Xu W, Modis LK, Lemieux RM. Horan JC, et al. Among authors: fisher mb. Bioorg Med Chem Lett. 2014 Oct 15;24(20):4807-11. doi: 10.1016/j.bmcl.2014.09.003. Epub 2014 Sep 6. Bioorg Med Chem Lett. 2014. PMID: 25241927

4

Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding.

Haining RL, Jones JP, Henne KR, Fisher MB, Koop DR, Trager WF, Rettie AE. Haining RL, et al. Among authors: fisher mb. Biochemistry. 1999 Mar 16;38(11):3285-92. doi: 10.1021/bi982161+. Biochemistry. 1999. PMID: 10079071

5

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A synthase by antibiotic 1233A and other beta-lactones.

Mayer RJ, Louis-Flamberg P, Elliott JD, Fisher M, Leber J. Mayer RJ, et al. Biochem Biophys Res Commun. 1990 Jun 15;169(2):610-6. doi: 10.1016/0006-291x(90)90374-v. Biochem Biophys Res Commun. 1990. PMID: 1972621

6

P450-catalyzed in-chain desaturation of valproic acid: isoform selectivity and mechanism of formation of Delta 3-valproic acid generated by baculovirus-expressed CYP3A1.

Fisher MB, Thompson SJ, Ribeiro V, Lechner MC, Rettie AE. Fisher MB, et al. Arch Biochem Biophys. 1998 Aug 1;356(1):63-70. doi: 10.1006/abbi.1998.0742. Arch Biochem Biophys. 1998. PMID: 9681992

7

Selectivity of flavin-containing monooxygenase 5 for the (S)-sulfoxidation of short-chain aralkyl sulfides.

Fisher MB, Lawton MP, Atta-Asafo-Adjei E, Philpot RM, Rettie AE. Fisher MB, et al. Drug Metab Dispos. 1995 Dec;23(12):1431-3. Drug Metab Dispos. 1995. PMID: 8689956 No abstract available.

8

Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid.

Sadeque AJ, Fisher MB, Korzekwa KR, Gonzalez FJ, Rettie AE. Sadeque AJ, et al. Among authors: fisher mb. J Pharmacol Exp Ther. 1997 Nov;283(2):698-703. J Pharmacol Exp Ther. 1997. PMID: 9353388

9

Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1.

Zheng YM, Fisher MB, Yokotani N, Fujii-Kuriyama Y, Rettie AE. Zheng YM, et al. Among authors: fisher mb. Biochemistry. 1998 Sep 15;37(37):12847-51. doi: 10.1021/bi981280m. Biochemistry. 1998. PMID: 9737862

10

Active site characteristics of CYP4B1 probed with aromatic ligands.

Henne KR, Fisher MB, Iyer KR, Lang DH, Trager WF, Rettie AE. Henne KR, et al. Among authors: fisher mb. Biochemistry. 2001 Jul 24;40(29):8597-605. doi: 10.1021/bi010395e. Biochemistry. 2001. PMID: 11456500

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