Chou LC - Search Results

1

Specific microtubule-depolymerizing agents augment efficacy of dendritic cell-based cancer vaccines.

Wen CC, Chen HM, Chen SS, Huang LT, Chang WT, Wei WC, Chou LC, Arulselvan P, Wu JB, Kuo SC, Yang NS. Wen CC, et al. Among authors: chou lc. J Biomed Sci. 2011 Jun 20;18(1):44. doi: 10.1186/1423-0127-18-44. J Biomed Sci. 2011. PMID: 21689407 Free PMC article.

2

KHC-4 anti-cancer effects on human PC3 prostate cancer cell line.

Hwang JM, Ting WJ, Wu HC, Chen YJ, Tsai FJ, Chen PY, Liu CY, Chou LC, Kuo SC, Huang CY. Hwang JM, et al. Among authors: chou lc. Am J Chin Med. 2012;40(5):1063-71. doi: 10.1142/S0192415X12500784. Am J Chin Med. 2012. PMID: 22928835

3

Synthesis of furopyrazole analogs of 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole (YC-1) as novel anti-leukemia agents.

Chou LC, Huang LJ, Yang JS, Lee FY, Teng CM, Kuo SC. Chou LC, et al. Bioorg Med Chem. 2007 Feb 15;15(4):1732-40. doi: 10.1016/j.bmc.2006.12.001. Epub 2006 Dec 6. Bioorg Med Chem. 2007. PMID: 17189698

4

The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells.

Chou LC, Yang JS, Huang LJ, Wu HC, Lu CC, Chiang JH, Chen KT, Kuo SC, Chung JG. Chou LC, et al. J Gastroenterol. 2009;44(10):1055-63. doi: 10.1007/s00535-009-0111-1. Epub 2009 Aug 14. J Gastroenterol. 2009. PMID: 19688288

5

Design, synthesis, and preclinical evaluation of new 5,6- (or 6,7-) disubstituted-2-(fluorophenyl)quinolin-4-one derivatives as potent antitumor agents.

Chou LC, Tsai MT, Hsu MH, Wang SH, Way TD, Huang CH, Lin HY, Qian K, Dong Y, Lee KH, Huang LJ, Kuo SC. Chou LC, et al. J Med Chem. 2010 Nov 25;53(22):8047-58. doi: 10.1021/jm100780c. Epub 2010 Oct 25. J Med Chem. 2010. PMID: 20973552

6

The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells.

Huang SM, Yang JS, Tsai SC, Chen MH, Hsu MH, Lin HY, Chou LC, Chinag JH, Lee KH, Huang LJ, Kuo SC. Huang SM, et al. Among authors: chou lc. Int J Oncol. 2011 May;38(5):1357-64. doi: 10.3892/ijo.2011.952. Epub 2011 Feb 22. Int J Oncol. 2011. PMID: 21344160

7

CHM-1 induces apoptosis via p38-mediated upregulation of DR5 expression in human ovarian cancer SKOV3 cells.

Lee JC, Chou LC, Huang CH, Chung JG, Huang LJ, Lee KH, Hung MC, Way TD, Kuo SC. Lee JC, et al. Among authors: chou lc. Eur J Pharmacol. 2011 Nov 16;670(1):96-104. doi: 10.1016/j.ejphar.2011.08.006. Epub 2011 Sep 3. Eur J Pharmacol. 2011. PMID: 21907193

8

CLC604 preferentially inhibits the growth of HER2-overexpressing cancer cells and sensitizes these cells to the inhibitory effect of Taxol in vitro and in vivo.

Lee JC, Chou LC, Lien JC, Wu JC, Huang CH, Chung CH, Lee FY, Huang LJ, Kuo SC, Way TD. Lee JC, et al. Among authors: chou lc. Oncol Rep. 2013 Oct;30(4):1762-72. doi: 10.3892/or.2013.2634. Epub 2013 Jul 23. Oncol Rep. 2013. PMID: 23900492

9

Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines.

Liu CY, Cheng YY, Chang LC, Huang LJ, Chou LC, Huang CH, Tsai MT, Liao CC, Hsu MH, Lin HY, Wu TS, Wen YF, Zhao Y, Kuo SC, Lee KH. Liu CY, et al. Among authors: chou lc. Eur J Med Chem. 2015 Jan 27;90:775-87. doi: 10.1016/j.ejmech.2014.11.062. Epub 2014 Dec 11. Eur J Med Chem. 2015. PMID: 25528332 Free PMC article.

10

Synthesis and in vitro anticancer activity of 6,7-methylenedioxy (or 5-hydroxy-6-methoxy)-2-(substituted selenophenyl)quinolin-4-one analogs.

Chen CT, Hsu MH, Cheng YY, Liu CY, Chou LC, Huang LJ, Wu TS, Yang X, Lee KH, Kuo SC. Chen CT, et al. Among authors: chou lc. Eur J Med Chem. 2011 Dec;46(12):6046-56. doi: 10.1016/j.ejmech.2011.10.017. Epub 2011 Oct 17. Eur J Med Chem. 2011. PMID: 22030314

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